HitPredict

Interactor 1: CREST (O75177)
Calcium-responsive transactivator (SS18-like protein 1) (SYT homolog 1)
Gene: SS18L1

Interactor 2: SMRD1 (Q96GM5)
SWI/SNF-related matrix-associated actin-dependent regulator of chromatin subfamily D member 1 (60 kDa BRG-1/Brm-associated factor subunit A) (BRG1-associated factor 60A) (BAF60A) (SWI/SNF complex 60 kDa subunit)
Gene: SMARCD1

Species: Homo sapiens

Source: intact

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.80	0.60	0.694

Property	Details
Experiments	26186194, 28514442, 24981860, 33961781
Identification Methods	affinity chromatography technology, anti tag coimmunoprecipitation
Interaction Type	physical association, association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0000776 - kinetochore GO:0003713 - transcription coactivator activity GO:0005634 - nucleus GO:0005654 - nucleoplasm GO:0071565 - nBAF complex
Homologous interactions	20

Homologous interactions (Top 20)

Color coding for hit scores

	1 396 Hs			1 515
+	Hs
		1074763 SSXT_HUMAN (1-396): 5.46e-68: 222: 53.83		SMRD1_HUMAN (1-515): 0: 696: 100.00
+	Hs
		257484 CREST_HUMAN (1-396): 3.15e-78: 248: 100.00		SMRD3_HUMAN (60-515): 0: 613: 74.35
+	Hs
		257510 CREST_HUMAN (1-396): 3.15e-78: 248: 100.00		SMRD2_HUMAN (51-515): 0: 601: 66.39
+	Mm
		1142595 SMCA2_MOUSE (74-384): 6.58e-36: 142: 17.93		SMRD1_MOUSE (1-515): 0: 696: 99.42
+	Hs
		1074745 SSXT_HUMAN (1-396): 5.46e-68: 222: 53.83		SMRD3_HUMAN (60-515): 0: 613: 74.35
+	Hs
		1292507 S18L2_HUMAN (1-73): 9.86e-40: 137: 60.27		SMRD1_HUMAN (1-515): 0: 696: 100.00
+	Hs
		1074760 SSXT_HUMAN (1-396): 5.46e-68: 222: 53.83		SMRD2_HUMAN (51-515): 0: 601: 66.39
+	Hs
		846849 SMCA2_HUMAN (74-384): 1.05e-26: 114: 15.67		SMRD1_HUMAN (1-515): 0: 696: 100.00
+	Mm
		1111927 SMCA4_MOUSE (74-384): 3.38e-11: 67.4: 12.96		SMRD1_MOUSE (1-515): 0: 696: 99.42
+	Hs
		847055 SMCA4_HUMAN (74-338): 1.2e-10: 65.5: 11.08		SMRD1_HUMAN (1-515): 0: 696: 100.00
+	Mm
		1150283 SMCA2_MOUSE (74-384): 6.58e-36: 142: 17.93		SMRD3_MOUSE (60-515): 0: 613: 74.35
+	Hs
		1164517 S18L2_HUMAN (1-73): 9.86e-40: 137: 60.27		SMRD3_HUMAN (60-515): 0: 613: 74.35
+	Hs
		1272996 S18L2_HUMAN (1-73): 9.86e-40: 137: 60.27		SMRD2_HUMAN (51-515): 0: 601: 66.39
+	Hs
		846803 SMCA2_HUMAN (74-384): 1.05e-26: 114: 15.67		SMRD3_HUMAN (60-515): 0: 613: 74.35
+	Hs
		846840 SMCA2_HUMAN (74-384): 1.05e-26: 114: 15.67		SMRD2_HUMAN (51-515): 0: 601: 66.39
+	Mm
		1111939 SMCA4_MOUSE (74-384): 3.38e-11: 67.4: 12.96		SMRD3_MOUSE (60-515): 0: 613: 74.35
+	Mm
		1111961 SMCA4_MOUSE (74-384): 3.38e-11: 67.4: 12.96		SMRD2_MOUSE (34-515): 0: 612: 65.33
+	Hs
		847000 SMCA4_HUMAN (74-338): 1.2e-10: 65.5: 11.08		SMRD3_HUMAN (60-515): 0: 613: 74.35
+	Hs
		847046 SMCA4_HUMAN (74-338): 1.2e-10: 65.5: 11.08		SMRD2_HUMAN (51-515): 0: 601: 66.39
+	Ce
		137207 RPB1_CAEEL (76-360): 2.63e-11: 67.8: 16.78		SWIC2_CAEEL (79-514): 0: 523: 50.34