HitPredict

Interactor 1: CREST (O75177)
Calcium-responsive transactivator (SS18-like protein 1) (SYT homolog 1)
Gene: SS18L1

Interactor 2: ELF5 (Q9UKW6)
ETS-related transcription factor Elf-5 (E74-like factor 5) (Epithelium-restricted ESE-1-related Ets factor) (Epithelium-specific Ets transcription factor 2) (ESE-2)
Gene: ELF5

Species: Homo sapiens

Source: intact

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.48	0.60	0.541

Property	Details
Experiments	20211142
Identification Methods	two hybrid, two hybrid array
Interaction Type	direct interaction, physical association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005634 - nucleus
Homologous interactions	20

Homologous interactions (Top 20)

Color coding for hit scores

	1 396 Hs			1 265
+	Hs
		1074778 SSXT_HUMAN (1-396): 5.46e-68: 222: 53.83		ELF5_HUMAN (1-265): 1.43e-113: 329: 100.00
+	Hs
		965404 SSXT_HUMAN (1-396): 5.46e-68: 222: 53.83		FLI1_HUMAN (35-255): 1.15e-70: 225: 24.34
+	Hs
		846894 SMCA2_HUMAN (74-384): 1.05e-26: 114: 15.67		ELF5_HUMAN (1-265): 1.43e-113: 329: 100.00
+	Hs
		257517 CREST_HUMAN (1-396): 3.15e-78: 248: 100.00		FEV_HUMAN (155-255): 1.2e-41: 144: 32.35
+	Hs
		794541 SSXT_HUMAN (1-396): 5.46e-68: 222: 53.83		ETV4_HUMAN (112-260): 1.52e-40: 147: 24.50
+	Hs
		257445 CREST_HUMAN (1-396): 3.15e-78: 248: 100.00		ERG_HUMAN (36-141): 5.06e-27: 110: 23.36
+	Hs
		257447 CREST_HUMAN (1-396): 3.15e-78: 248: 100.00		ETS1_HUMAN (22-167): 3.12e-27: 110: 17.69
+	Hs
		846751 SMCA2_HUMAN (74-384): 1.05e-26: 114: 15.67		FLI1_HUMAN (35-255): 1.15e-70: 225: 24.34
+	Hs
		846856 SMCA2_HUMAN (74-384): 1.05e-26: 114: 15.67		ELF4_HUMAN (1-264): 3.88e-68: 224: 21.17
+	Hs
		507433 SSXT_HUMAN (1-396): 5.46e-68: 222: 53.83		ERG_HUMAN (36-141): 5.06e-27: 110: 23.36
+	Hs
		846934 SMCA4_HUMAN (74-338): 1.2e-10: 65.5: 11.08		FLI1_HUMAN (35-255): 1.15e-70: 225: 24.34
+	Hs
		692114 SMCA2_HUMAN (74-384): 1.05e-26: 114: 15.67		ELF1_HUMAN (116-261): 3.1e-44: 159: 28.57
+	Hs
		794530 SMCA2_HUMAN (74-384): 1.05e-26: 114: 15.67		ETV4_HUMAN (112-260): 1.52e-40: 147: 24.50
+	Hs
		507385 SMCA2_HUMAN (74-384): 1.05e-26: 114: 15.67		ERG_HUMAN (36-141): 5.06e-27: 110: 23.36
+	Hs
		541992 SMCA2_HUMAN (74-384): 1.05e-26: 114: 15.67		ETS1_HUMAN (22-167): 3.12e-27: 110: 17.69
+	Mm
		542772 SMCA4_MOUSE (74-384): 3.38e-11: 67.4: 12.96		ETS2_MOUSE (1-170): 4.97e-37: 138: 18.44
+	Hs
		507386 SMCA4_HUMAN (74-338): 1.2e-10: 65.5: 11.08		ERG_HUMAN (36-141): 5.06e-27: 110: 23.36
+	Hs
		541993 SMCA4_HUMAN (74-338): 1.2e-10: 65.5: 11.08		ETS1_HUMAN (22-167): 3.12e-27: 110: 17.69
+	Hs
		507518 CHD7_HUMAN (39-357): 2.97e-09: 61.2: 11.83		ERG_HUMAN (36-141): 5.06e-27: 110: 23.36
+	Hs
		781237 CHD7_HUMAN (39-357): 2.97e-09: 61.2: 11.83		ETV3_HUMAN (174-256): 3.77e-13: 70.5: 41.67