Interactor 1: SIN3B (O75182)
Paired amphipathic helix protein Sin3b (Histone deacetylase complex subunit Sin3b) (Transcriptional corepressor Sin3b)
Gene: SIN3B

Interactor 2: SAP30 (O75446)
Histone deacetylase complex subunit SAP30 (30 kDa Sin3-associated polypeptide) (Sin3 corepressor complex subunit SAP30) (Sin3-associated polypeptide p30)
Gene: SAP30

Species: Homo sapiens

Source: intact

Category: Small-scale

Confidence: High

Method score Annotation score Interaction score
0.79 1.00 0.892

The method score is based on:

Property Details
Experiments 26496610, 24981860, 10444591, 33961781
Identification Methods affinity chromatography technology, biochemical, anti tag coimmunoprecipitation
Interaction Type physical association, association

The annotation score is based on:

Property Details
Interacting Pfam domains PAH~SAP30_Sin3_bdg
Common GO terms GO:0000118 - histone deacetylase complex
GO:0000122 - negative regulation of transcription by RNA polymerase II
GO:0003714 - transcription corepressor activity
GO:0005634 - nucleus
GO:0005654 - nucleoplasm
and 1 others

more...

Homologous interactions 4

Homologous interactions

Color coding for hit scores

1 1162
Hs

1 220
+ Mm
+ Hs
+ Mm
+ Hs

Service provided by Combinatics, Japan

Last updated: 15 Jul 2024