HitPredict

Interactor 1: SIN3B (O75182)
Paired amphipathic helix protein Sin3b (Histone deacetylase complex subunit Sin3b) (Transcriptional corepressor Sin3b)
Gene: SIN3B

Interactor 2: MTA1 (Q13330)
Metastasis-associated protein MTA1
Gene: MTA1

Species: Homo sapiens

Source: biogrid

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.38	0.60	0.479

Property	Details
Experiments	24981860
Identification Methods	affinity chromatography technology
Interaction Type	physical association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0000122 - negative regulation of transcription by RNA polymerase II GO:0003682 - chromatin binding GO:0003714 - transcription corepressor activity GO:0005634 - nucleus GO:0005654 - nucleoplasm and 1 others more... GO:0005737 - cytoplasm
Homologous interactions	7

Homologous interactions

Color coding for hit scores

	1 1162 Hs			1 715
+	Hs
		257731 SIN3B_HUMAN (1-1162): 0: 1453: 100.00		MTA2_HUMAN (1-715): 0: 741: 57.55
+	Hs
		257824 SIN3B_HUMAN (1-1162): 0: 1453: 100.00		MTA3_HUMAN (1-592): 0: 716: 68.98
+	Hs
		257847 SIN3B_HUMAN (1-1162): 0: 1453: 100.00		RCOR1_HUMAN (165-532): 5.9e-67: 230: 18.60
+	Hs
		1031933 SIN3A_HUMAN (78-366): 2.42e-15: 83.4: 15.60		MTA1_HUMAN (1-715): 0: 939: 100.00
+	Hs
		296108 SIN3A_HUMAN (78-366): 2.42e-15: 83.4: 15.60		MTA2_HUMAN (1-715): 0: 741: 57.55
+	Hs
		1302434 SIN3A_HUMAN (78-366): 2.42e-15: 83.4: 15.60		MTA3_HUMAN (1-592): 0: 716: 68.98
+	Hs
		1231965 SIN3A_HUMAN (78-366): 2.42e-15: 83.4: 15.60		MIER2_HUMAN (32-454): 4.87e-80: 267: 16.74