HitPredict

Interactor 1: SIN3B (O75182)
Paired amphipathic helix protein Sin3b (Histone deacetylase complex subunit Sin3b) (Transcriptional corepressor Sin3b)
Gene: SIN3B

Interactor 2: IKZF1 (Q13422)
DNA-binding protein Ikaros (Ikaros family zinc finger protein 1) (Lymphoid transcription factor LyF-1)
Gene: IKZF1

Species: Homo sapiens

Source: biogrid

Category: Small-scale

Confidence: High

Method score	Annotation score	Interaction score
0.56	0.60	0.584

Property	Details
Experiments	10357820, 12015313
Identification Methods	affinity chromatography technology
Interaction Type	physical association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005634 - nucleus GO:0005654 - nucleoplasm
Homologous interactions	7

Homologous interactions

Color coding for hit scores

	1 1162 Hs			1 519
+	Hs
		257848 SIN3B_HUMAN (1-1162): 0: 1453: 100.00		IKZF2_HUMAN (37-517): 1.17e-145: 430: 53.74
+	Hs
		257833 SIN3B_HUMAN (1-1162): 0: 1453: 100.00		IKZF4_HUMAN (28-515): 2.23e-142: 423: 51.26
+	Hs
		257849 SIN3B_HUMAN (1-1162): 0: 1453: 100.00		IKZF3_HUMAN (11-515): 4.42e-139: 413: 53.82
+	Hs
		1033714 SIN3A_HUMAN (78-366): 2.42e-15: 83.4: 15.60		IKZF1_HUMAN (1-519): 0: 664: 100.00
+	Hs
		1302473 SIN3A_HUMAN (78-366): 2.42e-15: 83.4: 15.60		IKZF2_HUMAN (37-517): 1.17e-145: 430: 53.74
+	Hs
		1302443 SIN3A_HUMAN (78-366): 2.42e-15: 83.4: 15.60		IKZF4_HUMAN (28-515): 2.23e-142: 423: 51.26
+	Hs
		1302474 SIN3A_HUMAN (78-366): 2.42e-15: 83.4: 15.60		IKZF3_HUMAN (11-515): 4.42e-139: 413: 53.82