HitPredict

Interactor 1: SIN3B (O75182)
Paired amphipathic helix protein Sin3b (Histone deacetylase complex subunit Sin3b) (Transcriptional corepressor Sin3b)
Gene: SIN3B

Interactor 2: RCOR1 (Q9UKL0)
REST corepressor 1 (Protein CoREST)
Gene: RCOR1

Species: Homo sapiens

Source: biogrid

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.38	0.60	0.479

Property	Details
Experiments	34709266
Identification Methods	proximity labelling technology
Interaction Type	physical association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0000118 - histone deacetylase complex GO:0003682 - chromatin binding GO:0003714 - transcription corepressor activity GO:0005634 - nucleus GO:0005654 - nucleoplasm
Homologous interactions	10

Homologous interactions

Color coding for hit scores

	1 1162 Hs			1 485
+	Hs
		257824 SIN3B_HUMAN (1-1162): 0: 1453: 100.00		MTA3_HUMAN (80-485): 5.88e-92: 293: 17.42
+	Hs
		257777 SIN3B_HUMAN (1-1162): 0: 1453: 100.00		MTA1_HUMAN (81-410): 5.09e-71: 241: 16.03
+	Hs
		257731 SIN3B_HUMAN (1-1162): 0: 1453: 100.00		MTA2_HUMAN (85-446): 1.69e-64: 222: 16.67
+	Hs
		1302434 SIN3A_HUMAN (78-366): 2.42e-15: 83.4: 15.60		MTA3_HUMAN (80-485): 5.88e-92: 293: 17.42
+	Hs
		1231965 SIN3A_HUMAN (78-366): 2.42e-15: 83.4: 15.60		MIER2_HUMAN (36-399): 5.54e-73: 242: 15.33
+	Hs
		1031933 SIN3A_HUMAN (78-366): 2.42e-15: 83.4: 15.60		MTA1_HUMAN (81-410): 5.09e-71: 241: 16.03
+	Hs
		296108 SIN3A_HUMAN (78-366): 2.42e-15: 83.4: 15.60		MTA2_HUMAN (85-446): 1.69e-64: 222: 16.67
+	Mm
		1141044 SIN3A_MOUSE (78-366): 2.73e-15: 83.4: 15.60		NCOR1_MOUSE (194-475): 6.78e-13: 73.5: 13.89
+	Hs
		261570 SIN3A_HUMAN (78-366): 2.42e-15: 83.4: 15.60		NCOR1_HUMAN (194-465): 5.18e-11: 67.4: 12.86
+	Hs
		1302485 SIN3A_HUMAN (78-366): 2.42e-15: 83.4: 15.60		NCOR2_HUMAN (194-380): 9.4e-09: 60.4: 12.11