HitPredict

Interactor 1: DNJB6 (O75190)
DnaJ homolog subfamily B member 6 (HHDJ1) (Heat shock protein J2) (HSJ-2) (MRJ) (MSJ-1)
Gene: DNAJB6

Interactor 2: BAG2 (O95816)
BAG family molecular chaperone regulator 2 (BAG-2) (Bcl-2-associated athanogene 2)
Gene: BAG2

Species: Homo sapiens

Source: intact

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.74	0.60	0.667

Property	Details
Experiments	33957083, 35271311, 25036637
Identification Methods	affinity chromatography technology, anti tag coimmunoprecipitation
Interaction Type	physical association, association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005829 - cytosol GO:0006457 - protein folding GO:0031072 - heat shock protein binding GO:0051087 - protein-folding chaperone binding
Homologous interactions	11

Homologous interactions

Color coding for hit scores

	1 326 Hs			1 211
+	Hs
		323863 DNJB7_HUMAN (1-300): 6.88e-100: 298: 55.00		BAG2_HUMAN (1-211): 3e-99: 288: 100.00
+	Hs
		279268 DNJB5_HUMAN (3-325): 3.42e-89: 272: 25.23		BAG2_HUMAN (1-211): 3e-99: 288: 100.00
+	Hs
		323596 DNJB1_HUMAN (3-325): 1.34e-87: 268: 26.19		BAG2_HUMAN (1-211): 3e-99: 288: 100.00
+	Hs
		324095 DNJB4_HUMAN (3-325): 2.32e-87: 267: 27.93		BAG2_HUMAN (1-211): 3e-99: 288: 100.00
+	Hs
		323926 DNJA4_HUMAN (4-324): 5.93e-84: 260: 23.84		BAG2_HUMAN (1-211): 3e-99: 288: 100.00
+	Hs
		323608 DNJA1_HUMAN (4-324): 1.03e-82: 257: 23.26		BAG2_HUMAN (1-211): 3e-99: 288: 100.00
+	Hs
		323910 DNJB8_HUMAN (1-231): 1.63e-84: 256: 59.31		BAG2_HUMAN (1-211): 3e-99: 288: 100.00
+	Hs
		243235 DNJA2_HUMAN (5-325): 2.37e-80: 252: 19.31		BAG2_HUMAN (1-211): 3e-99: 288: 100.00
+	Hs
		323597 DNJB2_HUMAN (1-322): 1.43e-77: 241: 45.23		BAG2_HUMAN (1-211): 3e-99: 288: 100.00
+	Dm
		1096123 DNAJ1_DROME (3-325): 5.05e-80: 248: 25.67		Q9VUQ1_DROME (7-178): 4.48e-73: 223: 35.64
+	Dm
		1096098 DNAJ1_DROME (3-325): 5.05e-80: 248: 25.67		Q95RY2_DROME (25-178): 8.85e-65: 202: 36.15