Interactor 1: DKC1 (O60832)
H/ACA ribonucleoprotein complex subunit DKC1 (EC 5.4.99.-) (CBF5 homolog) (Dyskerin) (Nopp140-associated protein of 57 kDa) (Nucleolar protein NAP57) (Nucleolar protein family A member 4) (snoRNP protein DKC1)
Gene: DKC1

Interactor 2: SPOUT (Q5T280)
28S rRNA (uridine-N(3))-methyltransferase (EC 2.1.1.-) (Centromere protein 32) (CENP-32) (Kinetochore-associated protein) (Methyltransferase C9orf114) (Ribosomal RNA methyltransferase SPOUT1) (SPOUT domain-containing methyltransferase 1)
Gene: SPOUT1

Species: Homo sapiens

Source: biogrid

Category: Small-scale

Confidence: High

Method score Annotation score Interaction score
0.38 0.60 0.479

The method score is based on:

Property Details
Experiments 26472758
Identification Methods affinity chromatography technology
Interaction Type physical association

The annotation score is based on:

Property Details
Interacting Pfam domains -
Common GO terms GO:0003723 - RNA binding
GO:0005737 - cytoplasm
Homologous interactions 2

Homologous interactions

Color coding for hit scores

1 514
Hs

1 376
+ Sc
+ Sc

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Last updated: 11Aug2025