HitPredict

Interactor 1: LRP5 (O75197)
Low-density lipoprotein receptor-related protein 5 (LRP-5) (Low-density lipoprotein receptor-related protein 7) (LRP-7)
Gene: LRP5

Interactor 2: FCGRN (P55899)
IgG receptor FcRn large subunit p51 (FcRn) (IgG Fc fragment receptor transporter alpha chain) (Neonatal Fc receptor)
Gene: FCGRT

Species: Homo sapiens

Source: intact

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.65	0.50	0.574

Property	Details
Experiments	28514442, 33961781
Identification Methods	affinity chromatography technology, anti tag coimmunoprecipitation
Interaction Type	physical association, association

Property	Details
Interacting Pfam domains	-
Common GO terms	-
Homologous interactions	5

Homologous interactions

Color coding for hit scores

	1 1615 Hs			1 365
+	Hs
		258295 LRP5_HUMAN (27-1615): 0: 1840: 100.00		HLAG_HUMAN (1-307): 6.38e-133: 384: 27.36
+	Hs
		270262 LRP6_HUMAN (8-646): 0: 590: 37.98		HLAG_HUMAN (1-307): 6.38e-133: 384: 27.36
+	Hs
		270278 LRP6_HUMAN (8-646): 0: 590: 37.98		FCGRN_HUMAN (1-365): 7.52e-116: 342: 100.00
+	Hs
		254251 LRP4_HUMAN (1358-1590): 1.14e-11: 72.4: 10.04		FCGRN_HUMAN (1-365): 7.52e-116: 342: 100.00
+	Hs
		351058 LDLR_HUMAN (1182-1295): 3.76e-11: 70.1: 19.30		FCGRN_HUMAN (1-365): 7.52e-116: 342: 100.00