HitPredict

Interactor 1: LRP5 (O75197)
Low-density lipoprotein receptor-related protein 5 (LRP-5) (Low-density lipoprotein receptor-related protein 7) (LRP-7)
Gene: LRP5

Interactor 2: ZN383 (Q8NA42)
Zinc finger protein 383
Gene: ZNF383

Species: Homo sapiens

Source: intact

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.47	0.50	0.489

Property	Details
Experiments	33961781
Identification Methods	affinity chromatography technology, anti tag coimmunoprecipitation
Interaction Type	physical association, association

Property	Details
Interacting Pfam domains	-
Common GO terms	-
Homologous interactions	11

Homologous interactions

Color coding for hit scores

	1 1615 Hs			1 475
+	Hs
		270315 LRP6_HUMAN (8-646): 0: 590: 37.98		ZN383_HUMAN (43-279): 1.91e-98: 305: 37.55
+	Hs
		254273 LRP4_HUMAN (1358-1590): 1.14e-11: 72.4: 10.04		ZNF34_HUMAN (2-475): 0: 606: 44.51
+	Hs
		1223925 SORL_HUMAN (1357-1615): 2.37e-10: 68.2: 9.36		ZNF34_HUMAN (2-475): 0: 606: 44.51
+	Hs
		254261 LRP4_HUMAN (1358-1590): 1.14e-11: 72.4: 10.04		ZNF74_HUMAN (65-393): 8.18e-142: 422: 41.34
+	Hs
		1083635 SORL_HUMAN (1357-1615): 2.37e-10: 68.2: 9.36		ZNF74_HUMAN (65-393): 8.18e-142: 422: 41.34
+	Hs
		254278 LRP4_HUMAN (1358-1590): 1.14e-11: 72.4: 10.04		ZN383_HUMAN (43-279): 1.91e-98: 305: 37.55
+	Hs
		200250 LRP2_HUMAN (1165-1411): 1.07e-11: 72.4: 11.33		ZN264_HUMAN (58-293): 5.02e-85: 275: 36.02
+	Hs
		200259 SORL_HUMAN (1357-1615): 2.37e-10: 68.2: 9.36		ZN264_HUMAN (58-293): 5.02e-85: 275: 36.02
+	Hs
		254295 LRP4_HUMAN (1358-1590): 1.14e-11: 72.4: 10.04		ZN331_HUMAN (150-360): 7.42e-73: 239: 59.72
+	Hs
		1269026 SORL_HUMAN (1357-1615): 2.37e-10: 68.2: 9.36		ZN331_HUMAN (150-360): 7.42e-73: 239: 59.72
+	Hs
		1343927 LRP1B_HUMAN (1254-1402): 6.09e-09: 63.5: 24.54		ZN331_HUMAN (150-360): 7.42e-73: 239: 59.72