HitPredict

Interactor 1: LRP5 (O75197)
Low-density lipoprotein receptor-related protein 5 (LRP-5) (Low-density lipoprotein receptor-related protein 7) (LRP-7)
Gene: LRP5

Interactor 2: RHES (Q96D21)
GTP-binding protein Rhes (Ras homolog enriched in striatum) (Tumor endothelial marker 2)
Gene: RASD2

Species: Homo sapiens

Source: intact

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.74	0.60	0.667

Property	Details
Experiments	26186194, 28514442, 33961781
Identification Methods	affinity chromatography technology, anti tag coimmunoprecipitation
Interaction Type	physical association, association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005886 - plasma membrane
Homologous interactions	6

Homologous interactions

Color coding for hit scores

	1 1615 Hs			1 266
+	Hs
		270319 LRP6_HUMAN (8-646): 0: 590: 37.98		RHES_HUMAN (1-266): 2.63e-83: 252: 100.00
+	Hs
		957607 LRP2_HUMAN (1165-1411): 1.07e-11: 72.4: 11.33		RAB35_HUMAN (12-195): 4.56e-83: 249: 29.19
+	Hs
		254254 LRP4_HUMAN (1358-1590): 1.14e-11: 72.4: 10.04		RB11A_HUMAN (10-222): 5.16e-73: 224: 20.80
+	Hs
		914007 LRP2_HUMAN (1165-1411): 1.07e-11: 72.4: 11.33		RB11A_HUMAN (10-222): 5.16e-73: 224: 20.80
+	Hs
		914062 LRP8_HUMAN (1186-1295): 6.43e-11: 69.7: 20.91		RB11A_HUMAN (10-222): 5.16e-73: 224: 20.80
+	Hs
		914028 LRP1_HUMAN (1216-1381): 3.14e-09: 64.3: 19.89		RB11A_HUMAN (10-222): 5.16e-73: 224: 20.80