HitPredict

Interactor 1: RTN2 (O75298)
Reticulon-2 (Neuroendocrine-specific protein-like 1) (NSP-like protein 1) (Neuroendocrine-specific protein-like I) (NSP-like protein I) (NSPLI)
Gene: RTN2

Interactor 2: RTN1 (Q16799)
Reticulon-1 (Neuroendocrine-specific protein)
Gene: RTN1

Species: Homo sapiens

Source: intact

Category: High-throughput

Confidence: High

Method score Annotation score Interaction score
0.65 0.60 0.628

The method score is based on:

Property Details
Experiments 28514442, 33961781
Identification Methods affinity chromatography technology, anti tag coimmunoprecipitation
Interaction Type physical association, association

The annotation score is based on:

Property Details
Interacting Pfam domains -
Common GO terms GO:0005783 - endoplasmic reticulum
GO:0005789 - endoplasmic reticulum membrane
GO:1902430 - negative regulation of amyloid-beta formation
Homologous interactions 16

Homologous interactions

Color coding for hit scores

1 545
Hs

1 776
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Last updated: 15 Jul 2024