HitPredict

Interactor 1: CAD16 (O75309)
Cadherin-16 (Kidney-specific cadherin) (Ksp-cadherin)
Gene: CDH16

Interactor 2: PTPRF (P10586)
Receptor-type tyrosine-protein phosphatase F (EC 3.1.3.48) (Leukocyte common antigen related) (LAR)
Gene: PTPRF

Species: Homo sapiens

Source: intact

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.47	0.60	0.536

Property	Details
Experiments	33961781
Identification Methods	affinity chromatography technology, anti tag coimmunoprecipitation
Interaction Type	physical association, association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0007155 - cell adhesion GO:0070062 - extracellular exosome
Homologous interactions	20

Homologous interactions (Top 20)

Color coding for hit scores

	1 829 Hs			1 1907
+	Hs
		259206 CAD16_HUMAN (1-829): 0: 685: 100.00		PTPRS_HUMAN (1-1907): 0: 1581: 65.73
+	Hs
		617032 PCDGG_HUMAN (2-441): 1.12e-84: 291: 19.18		PTPRD_HUMAN (29-1907): 0: 1573: 69.46
+	Hs
		490028 PCDBG_HUMAN (453-800): 3.82e-43: 170: 13.28		PTPRF_HUMAN (1-1907): 0: 1662: 100.00
+	Hs
		490044 PCDGD_HUMAN (2-228): 1.03e-42: 169: 22.69		PTPRF_HUMAN (1-1907): 0: 1662: 100.00
+	Hs
		1032047 PCDG7_HUMAN (1-328): 5.43e-66: 239: 19.43		PTPRS_HUMAN (1-1907): 0: 1581: 65.73
+	Hs
		1032046 PCDGD_HUMAN (2-228): 1.03e-42: 169: 22.69		PTPRS_HUMAN (1-1907): 0: 1581: 65.73
+	Hs
		617033 PCDB6_HUMAN (456-798): 4.28e-44: 173: 14.13		PTPRD_HUMAN (29-1907): 0: 1573: 69.46
+	Hs
		617023 PCDBG_HUMAN (453-800): 3.82e-43: 170: 13.28		PTPRD_HUMAN (29-1907): 0: 1573: 69.46
+	Hs
		616974 DSC3_HUMAN (19-454): 6.89e-25: 113: 25.36		PTPRD_HUMAN (29-1907): 0: 1573: 69.46
+	Dm
		183403 CADN_DROME (280-748): 4.69e-33: 140: 13.54		LAR_DROME (1-1339): 1.18e-170: 573: 32.75
+	Mm
		1351667 CAD17_MOUSE (3-655): 3.04e-85: 290: 16.36		S4R1M0_MOUSE (692-1636): 2.44e-82: 298: 16.88
+	Hs
		1123263 PCDGD_HUMAN (2-228): 1.03e-42: 169: 22.69		SDK2_HUMAN (165-1102): 1.35e-112: 401: 20.04
+	Hs
		1269195 PCDB7_HUMAN (3-464): 9.61e-90: 302: 21.81		PTPRU_HUMAN (238-855): 4.89e-31: 136: 14.44
+	Hs
		1269189 PCDGG_HUMAN (2-441): 1.12e-84: 291: 19.18		PTPRU_HUMAN (238-855): 4.89e-31: 136: 14.44
+	Hs
		1069992 PCDGG_HUMAN (2-441): 1.12e-84: 291: 19.18		PTPRK_HUMAN (116-656): 8.46e-16: 86.2: 14.41
+	Hs
		1269196 PCDB3_HUMAN (271-797): 6.76e-61: 222: 18.61		PTPRU_HUMAN (238-855): 4.89e-31: 136: 14.44
+	Hs
		1269198 PCDGD_HUMAN (2-228): 1.03e-42: 169: 22.69		PTPRU_HUMAN (238-855): 4.89e-31: 136: 14.44
+	Hs
		1069995 PCDGD_HUMAN (2-228): 1.03e-42: 169: 22.69		PTPRK_HUMAN (116-656): 8.46e-16: 86.2: 14.41
+	Mm
		472760 CADH2_MOUSE (4-237): 9.24e-19: 93.5: 15.55		PTPRQ_MOUSE (773-1388): 3.55e-30: 133: 15.27
+	Rn
		94056 CADH2_RAT (4-237): 3.5e-18: 91.6: 15.55		F1LPJ1_RAT (105-534): 5.15e-17: 90: 14.22