HitPredict

Interactor 1: LRRN2 (O75325)
Leucine-rich repeat neuronal protein 2 (Glioma amplified on chromosome 1 protein) (Leucine-rich repeat neuronal protein 5)
Gene: LRRN2

Interactor 2: CLC4A (Q9UMR7)
C-type lectin domain family 4 member A (C-type lectin DDB27) (C-type lectin superfamily member 6) (Dendritic cell immunoreceptor) (Lectin-like immunoreceptor) (CD antigen CD367)
Gene: CLEC4A

Species: Homo sapiens

Source: intact

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.47	1.00	0.691

Property	Details
Experiments	33961781
Identification Methods	affinity chromatography technology, anti tag coimmunoprecipitation
Interaction Type	physical association, association

Property	Details
Interacting Pfam domains	LRR_8~Lectin_C
Common GO terms	GO:0007155 - cell adhesion
Homologous interactions	17

Homologous interactions

Color coding for hit scores

	1 713 Hs			1 237
+	Hs
		1166673 LRIG3_HUMAN (2-702): 1.57e-104: 346: 19.26		CLC4A_HUMAN (1-237): 9.8e-70: 215: 100.00
+	Hs
		299599 LRIG2_HUMAN (2-702): 2.78e-101: 336: 18.93		CLC4E_HUMAN (25-236): 9.51e-58: 184: 34.58
+	Hs
		299573 LRIG2_HUMAN (2-702): 2.78e-101: 336: 18.93		CLC4D_HUMAN (31-237): 3.03e-54: 175: 33.33
+	Hs
		1100734 LRIG3_HUMAN (2-702): 1.57e-104: 346: 19.26		CL12B_HUMAN (1-232): 5.06e-45: 153: 17.82
+	Hs
		1291088 LIGO1_HUMAN (2-531): 7.04e-83: 276: 24.35		CLC4A_HUMAN (1-237): 9.8e-70: 215: 100.00
+	Hs
		299565 LRIG2_HUMAN (2-702): 2.78e-101: 336: 18.93		CL12B_HUMAN (1-232): 5.06e-45: 153: 17.82
+	Hs
		1263883 LRIG1_HUMAN (58-710): 1.96e-90: 307: 16.79		CLC4D_HUMAN (31-237): 3.03e-54: 175: 33.33
+	Hs
		1100785 LRIG1_HUMAN (58-710): 1.96e-90: 307: 16.79		CL12B_HUMAN (1-232): 5.06e-45: 153: 17.82
+	Hs
		644626 LRIG1_HUMAN (58-710): 1.96e-90: 307: 16.79		NKG2A_HUMAN (2-233): 1.65e-40: 140: 16.81
+	Hs
		1268547 PXDN_HUMAN (213-706): 3.53e-60: 222: 16.96		CLC4A_HUMAN (1-237): 9.8e-70: 215: 100.00
+	Hs
		1100782 LIGO1_HUMAN (2-531): 7.04e-83: 276: 24.35		CL12B_HUMAN (1-232): 5.06e-45: 153: 17.82
+	Hs
		1166424 LRC4C_HUMAN (2-296): 1.99e-69: 241: 27.70		CLC4G_HUMAN (70-232): 1.34e-39: 139: 27.22
+	Hs
		1350024 LRFN1_HUMAN (21-233): 8.15e-39: 156: 28.04		CLC4A_HUMAN (1-237): 9.8e-70: 215: 100.00
+	Hs
		296667 SLIT2_HUMAN (189-496): 1.69e-29: 127: 23.70		CLC4D_HUMAN (31-237): 3.03e-54: 175: 33.33
+	Hs
		644647 LRFN1_HUMAN (21-233): 8.15e-39: 156: 28.04		NKG2A_HUMAN (2-233): 1.65e-40: 140: 16.81
+	Hs
		644631 LGR4_HUMAN (45-325): 8.08e-35: 144: 18.57		NKG2A_HUMAN (2-233): 1.65e-40: 140: 16.81
+	Hs
		1100740 R4RL2_HUMAN (142-450): 5.72e-17: 85.9: 30.10		CL12B_HUMAN (1-232): 5.06e-45: 153: 17.82