HitPredict

Interactor 1: PDCD6 (O75340)
Programmed cell death protein 6 (Apoptosis-linked gene 2 protein homolog) (ALG-2)
Gene: PDCD6

Interactor 2: MYC (P01106)
Myc proto-oncogene protein (Class E basic helix-loop-helix protein 39) (bHLHe39) (Proto-oncogene c-Myc) (Transcription factor p64)
Gene: MYC

Species: Homo sapiens

Source: intact

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.62	0.60	0.611

Property	Details
Experiments	26496610, 35013218
Identification Methods	affinity chromatography technology, anti tag coimmunoprecipitation
Interaction Type	physical association, association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005634 - nucleus GO:0005654 - nucleoplasm GO:0005737 - cytoplasm GO:0043280 - positive regulation of cysteine-type endopeptidase activity involved in apoptotic process GO:0046983 - protein dimerization activity
Homologous interactions	9

Homologous interactions

Color coding for hit scores

	1 191 Hs			1 454
+	Hs
		345710 CAN1_HUMAN (19-188): 3.38e-52: 179: 22.58		MYC_HUMAN (1-454): 1.73e-122: 366: 100.00
+	Hs
		345862 CAN2_HUMAN (28-191): 3.7e-51: 176: 24.56		MYC_HUMAN (1-454): 1.73e-122: 366: 100.00
+	Hs
		346032 SORCN_HUMAN (25-190): 1.79e-51: 165: 35.88		MYC_HUMAN (1-454): 1.73e-122: 366: 100.00
+	Hs
		345983 CALL3_HUMAN (94-189): 3.78e-25: 96.8: 18.45		MYC_HUMAN (1-454): 1.73e-122: 366: 100.00
+	Hs
		348092 CALL5_HUMAN (18-151): 2.44e-12: 63.2: 30.22		MYC_HUMAN (1-454): 1.73e-122: 366: 100.00
+	Hs
		379050 SORCN_HUMAN (25-190): 1.79e-51: 165: 35.88		MYCN_HUMAN (12-451): 9.39e-59: 201: 33.40
+	Hs
		259681 PDCD6_HUMAN (1-191): 1.36e-46: 153: 100.00		MYCN_HUMAN (12-451): 9.39e-59: 201: 33.40
+	Hs
		648510 CALL3_HUMAN (94-189): 3.78e-25: 96.8: 18.45		USF2_HUMAN (180-454): 1.78e-35: 136: 15.99
+	Hs
		1079729 CALL5_HUMAN (18-151): 2.44e-12: 63.2: 30.22		USF2_HUMAN (180-454): 1.78e-35: 136: 15.99