HitPredict

Interactor 1: PDCD6 (O75340)
Programmed cell death protein 6 (Apoptosis-linked gene 2 protein homolog) (ALG-2)
Gene: PDCD6

Interactor 2: CFTR (P13569)
Cystic fibrosis transmembrane conductance regulator (CFTR) (ATP-binding cassette sub-family C member 7) (Channel conductance-controlling ATPase) (EC 5.6.1.6) (cAMP-dependent chloride channel)
Gene: CFTR

Species: Homo sapiens

Source: intact

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.68	0.60	0.643

Property	Details
Experiments	17110338, 31324722, 26618866
Identification Methods	affinity chromatography technology, anti bait coimmunoprecipitation, cross-linking study
Interaction Type	physical association, association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005634 - nucleus GO:0005737 - cytoplasm GO:0005789 - endoplasmic reticulum membrane GO:0005829 - cytosol
Homologous interactions	6

Homologous interactions

Color coding for hit scores

	1 191 Hs			1 1480
+	Hs
		427833 CAN1_HUMAN (19-188): 3.38e-52: 179: 22.58		CFTR_HUMAN (1-1480): 0: 1031: 100.00
+	Hs
		528495 CAN2_HUMAN (28-191): 3.7e-51: 176: 24.56		CFTR_HUMAN (1-1480): 0: 1031: 100.00
+	Hs
		385833 CPNS1_HUMAN (2-188): 1.15e-46: 155: 25.38		CFTR_HUMAN (1-1480): 0: 1031: 100.00
+	Hs
		484052 CALM3_HUMAN (91-189): 1.6e-26: 100: 20.76		CFTR_HUMAN (1-1480): 0: 1031: 100.00
+	Hs
		528591 CALL3_HUMAN (94-189): 3.78e-25: 96.8: 18.45		CFTR_HUMAN (1-1480): 0: 1031: 100.00
+	Hs
		529820 CALL5_HUMAN (18-151): 2.44e-12: 63.2: 30.22		CFTR_HUMAN (1-1480): 0: 1031: 100.00