HitPredict

Interactor 1: VATG1 (O75348)
V-type proton ATPase subunit G 1 (V-ATPase subunit G 1) (V-ATPase 13 kDa subunit 1) (Vacuolar proton pump subunit G 1) (Vacuolar proton pump subunit M16)
Gene: ATP6V1G1

Interactor 2: VATC1 (P21283)
V-type proton ATPase subunit C 1 (V-ATPase subunit C 1) (Vacuolar proton pump subunit C 1)
Gene: ATP6V1C1

Species: Homo sapiens

Source: intact

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.62	1.00	0.789

The method score is based on:

Property	Details
Experiments	33961781, 35271311
Identification Methods	affinity chromatography technology, anti tag coimmunoprecipitation
Interaction Type	physical association, association

The annotation score is based on:

Property	Details
Interacting Pfam domains	V-ATPase_C~V-ATPase_G
Common GO terms	GO:0000221 - vacuolar proton-transporting V-type ATPase, V1 domain GO:0005765 - lysosomal membrane GO:0005829 - cytosol GO:0005886 - plasma membrane GO:0016241 - regulation of macroautophagy and 4 others more... GO:0046961 - proton-transporting ATPase activity, rotational mechanism GO:0070062 - extracellular exosome GO:0097401 - synaptic vesicle lumen acidification GO:1902495 - transmembrane transporter complex
Homologous interactions	4

Homologous interactions

Color coding for hit scores

	1	118
Hs

1	382

Service provided by Combinatics, Japan

Last updated: 15 Jul 2024