HitPredict

Interactor 1: VPS4B (O75351)
Vacuolar protein sorting-associated protein 4B (EC 3.6.4.6) (Cell migration-inducing gene 1 protein) (Suppressor of K(+) transport growth defect 1) (Protein SKD1)
Gene: VPS4B

Interactor 2: VPS4A (Q9UN37)
Vacuolar protein sorting-associated protein 4A (EC 3.6.4.6) (Protein SKD2) (VPS4-1) (hVPS4)
Gene: VPS4A

Species: Homo sapiens

Source: intact

Category: High-throughput

Confidence: High

Method score Annotation score Interaction score
0.74 1.00 0.861

The method score is based on:

Property Details
Experiments 26186194, 28514442, 33961781
Identification Methods affinity chromatography technology, anti tag coimmunoprecipitation
Interaction Type physical association, association

The annotation score is based on:

Property Details
Interacting Pfam domains AAA~AAA, AAA~AAA_lid_3, AAA~Vps4_C, AAA_lid_3~AAA_lid_3, AAA_lid_3~Vps4_C, MIT~MIT, Vps4_C~Vps4_C
Common GO terms GO:0000922 - spindle pole
GO:0001778 - plasma membrane repair
GO:0005524 - ATP binding
GO:0005634 - nucleus
GO:0005643 - nuclear pore
and 33 others

more...
Homologous interactions 18

Homologous interactions

Color coding for hit scores

1 444
Hs

1 437
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Service provided by Combinatics, Japan

Last updated: 15 Jul 2024