HitPredict

Interactor 1: PROP1 (O75360)
Homeobox protein prophet of Pit-1 (PROP-1) (Pituitary-specific homeodomain factor)
Gene: PROP1

Interactor 2: ATN1 (P54259)
Atrophin-1 (Dentatorubral-pallidoluysian atrophy protein)
Gene: ATN1

Species: Homo sapiens

Source: intact

Category: Small-scale

Confidence: High

Method score	Annotation score	Interaction score
0.34	0.60	0.457

Property	Details
Experiments	23732115
Identification Methods	two hybrid
Interaction Type	physical association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005634 - nucleus GO:0007417 - central nervous system development GO:0016477 - cell migration
Homologous interactions	12

Homologous interactions

Color coding for hit scores

	1 226 Hs			1 1190
+	Hs
		869449 PITX1_HUMAN (16-212): 8.33e-29: 111: 23.42		ATN1_HUMAN (1-1190): 1.67e-152: 490: 100.00
+	Hs
		1200894 LMX1A_HUMAN (16-208): 4.9e-29: 113: 21.29		Q86V38_HUMAN (1-1190): 4.18e-151: 486: 98.83
+	Hs
		941923 PITX1_HUMAN (16-212): 8.33e-29: 111: 23.42		Q86V38_HUMAN (1-1190): 4.18e-151: 486: 98.83
+	Hs
		620175 PAX7_HUMAN (52-223): 2.86e-32: 124: 28.02		KMT2C_HUMAN (73-701): 1.56e-19: 97.8: 17.13
+	Hs
		641482 PAX6_HUMAN (19-224): 2.6e-30: 117: 24.77		KMT2C_HUMAN (73-701): 1.56e-19: 97.8: 17.13
+	Hs
		839785 LHX2_HUMAN (19-201): 7.83e-29: 113: 21.31		KMT2C_HUMAN (73-701): 1.56e-19: 97.8: 17.13
+	Hs
		641457 PAX6_HUMAN (19-224): 2.6e-30: 117: 24.77		SRCAP_HUMAN (327-1016): 7.44e-14: 79.1: 12.90
+	Hs
		620215 PAX7_HUMAN (52-223): 2.86e-32: 124: 28.02		CHD7_HUMAN (6-367): 3.27e-10: 67.1: 13.30
+	Hs
		641410 PAX6_HUMAN (19-224): 2.6e-30: 117: 24.77		NCOA6_HUMAN (260-799): 2.05e-10: 67.5: 8.99
+	Hs
		641583 PAX6_HUMAN (19-224): 2.6e-30: 117: 24.77		CHD7_HUMAN (6-367): 3.27e-10: 67.1: 13.30
+	Hs
		203210 PAX6_HUMAN (19-224): 2.6e-30: 117: 24.77		SYNJ1_HUMAN (515-960): 3.78e-09: 63.6: 15.66
+	Hs
		839836 LHX2_HUMAN (19-201): 7.83e-29: 113: 21.31		CHD7_HUMAN (6-367): 3.27e-10: 67.1: 13.30