HitPredict

Interactor 1: PROP1 (O75360)
Homeobox protein prophet of Pit-1 (PROP-1) (Pituitary-specific homeodomain factor)
Gene: PROP1

Interactor 2: SUMO1 (P63165)
Small ubiquitin-related modifier 1 (SUMO-1) (GAP-modifying protein 1) (GMP1) (SMT3 homolog 3) (Sentrin) (Ubiquitin-homology domain protein PIC1) (Ubiquitin-like protein SMT3C) (Smt3C) (Ubiquitin-like protein UBL1)
Gene: SUMO1

Species: Homo sapiens

Source: intact

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.61	0.60	0.606

Property	Details
Experiments	32296183, unassigned1304
Identification Methods	two hybrid, two hybrid prey pooling approach, two hybrid array, validated two hybrid
Interaction Type	direct interaction, physical association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005634 - nucleus
Homologous interactions	4

Homologous interactions

Color coding for hit scores

	1 226 Hs			1 101
+	Hs
		641367 PAX6_HUMAN (19-224): 2.6e-30: 117: 24.77		SUMO1_HUMAN (1-101): 1.01e-41: 134: 100.00
+	Mm
		926105 PAX6_MOUSE (19-224): 2.6e-30: 117: 24.77		SUMO1_MOUSE (1-101): 1.01e-41: 134: 100.00
+	Hs
		641356 PAX6_HUMAN (19-224): 2.6e-30: 117: 24.77		SUMO3_HUMAN (1-97): 1.65e-37: 123: 47.42
+	Ce
		589682 LIN11_CAEEL (1-213): 2.08e-31: 120: 21.40		SUMO_CAEEL (9-97): 4.4e-34: 114: 58.43