HitPredict

Interactor 1: ZN217 (O75362)
Zinc finger protein 217
Gene: ZNF217

Interactor 2: HDAC2 (Q92769)
Histone deacetylase 2 (HD2) (EC 3.5.1.98) (Protein deacylase HDAC2) (EC 3.5.1.-)
Gene: HDAC2

Species: Homo sapiens

Source: intact

Category: Small-scale

Confidence: High

Method score	Annotation score	Interaction score
0.84	0.60	0.714

Property	Details
Experiments	27684187, 18625718, 17967884, 35271311, 23752268
Identification Methods	affinity chromatography technology, anti tag coimmunoprecipitation
Interaction Type	physical association, association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0000118 - histone deacetylase complex GO:0000122 - negative regulation of transcription by RNA polymerase II GO:0005634 - nucleus GO:0005654 - nucleoplasm GO:0045892 - negative regulation of DNA-templated transcription
Homologous interactions	4

Homologous interactions

Color coding for hit scores

	1 1048 Hs			1 488
+	Hs
		260378 ZN217_HUMAN (1-1048): 0: 851: 100.00		HDAC1_HUMAN (1-443): 0: 642: 90.07
+	Hs
		1268295 ZN516_HUMAN (60-451): 1.79e-48: 190: 33.95		HDAC2_HUMAN (1-488): 0: 707: 100.00
+	Hs
		1038587 ZN516_HUMAN (60-451): 1.79e-48: 190: 33.95		HDAC1_HUMAN (1-443): 0: 642: 90.07
+	Hs
		167156 ZN536_HUMAN (473-521): 1.36e-09: 64.7: 57.14		HDAC1_HUMAN (1-443): 0: 642: 90.07