HitPredict

Interactor 1: PITX3 (O75364)
Pituitary homeobox 3 (Homeobox protein PITX3) (Paired-like homeodomain transcription factor 3)
Gene: PITX3

Interactor 2: NONO (Q15233)
Non-POU domain-containing octamer-binding protein (NonO protein) (54 kDa nuclear RNA- and DNA-binding protein) (p54(nrb)) (p54nrb) (55 kDa nuclear protein) (NMT55) (DNA-binding p52/p100 complex, 52 kDa subunit)
Gene: NONO

Species: Homo sapiens

Source: biogrid

Category: Small-scale

Confidence: High

Method score	Annotation score	Interaction score
0.38	0.60	0.479

Property	Details
Experiments	19144721
Identification Methods	affinity chromatography technology
Interaction Type	physical association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005634 - nucleus GO:0006355 - regulation of DNA-templated transcription
Homologous interactions	6

Homologous interactions

Color coding for hit scores

	1 302 Hs			1 471
+	Hs
		260475 PITX3_HUMAN (1-302): 3.03e-56: 185: 100.00		SFPQ_HUMAN (45-471): 3.15e-53: 192: 56.92
+	Mm
		665766 Q8VD35_MOUSE (44-281): 1.47e-32: 123: 27.73		PABP1_MOUSE (66-459): 9.31e-65: 222: 14.89
+	Hs
		516407 LHX1_HUMAN (2-288): 1.1e-30: 120: 17.59		PABP1_HUMAN (66-459): 7.11e-65: 222: 14.89
+	Mm
		1257442 Q8VD35_MOUSE (44-281): 1.47e-32: 123: 27.73		SFPQ_MOUSE (23-471): 7.21e-54: 193: 55.72
+	Hs
		1300554 ARX_HUMAN (32-294): 8.14e-31: 123: 31.70		RBM4_HUMAN (75-182): 7.64e-09: 59.3: 35.71
+	Hs
		641550 PAX6_HUMAN (17-257): 1.3e-31: 123: 22.66		RBM4_HUMAN (75-182): 7.64e-09: 59.3: 35.71