HitPredict

Interactor 1: TP4A3 (O75365)
Protein tyrosine phosphatase type IVA 3 (EC 3.1.3.48) (PRL-R) (Protein-tyrosine phosphatase 4a3) (Protein-tyrosine phosphatase of regenerating liver 3) (PRL-3)
Gene: PTP4A3

Interactor 2: MYO1D (O94832)
Unconventional myosin-Id
Gene: MYO1D

Species: Homo sapiens

Source: intact

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.47	0.60	0.536

Property	Details
Experiments	33961781
Identification Methods	affinity chromatography technology, anti tag coimmunoprecipitation
Interaction Type	physical association, association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005737 - cytoplasm GO:0005769 - early endosome GO:0005886 - plasma membrane
Homologous interactions	12

Homologous interactions

Color coding for hit scores

	1 173 Hs			1 1006
+	Hs
		297327 PTEN_HUMAN (5-163): 2.34e-41: 144: 18.86		MYO1D_HUMAN (1-1006): 0: 1178: 100.00
+	Hs
		117531 TP4A3_HUMAN (1-173): 7.13e-57: 177: 100.00		MYO1C_HUMAN (8-926): 0: 1030: 41.06
+	Hs
		260637 TP4A3_HUMAN (1-173): 7.13e-57: 177: 100.00		MYO5B_HUMAN (3-1006): 0: 1005: 28.90
+	Hs
		260644 TP4A3_HUMAN (1-173): 7.13e-57: 177: 100.00		MYO5A_HUMAN (3-996): 0: 1003: 30.54
+	Hs
		117646 PTEN_HUMAN (5-163): 2.34e-41: 144: 18.86		MYO1C_HUMAN (8-926): 0: 1030: 41.06
+	Hs
		117512 GAK_HUMAN (9-151): 1.05e-38: 141: 17.42		MYO1C_HUMAN (8-926): 0: 1030: 41.06
+	Hs
		260524 TP4A3_HUMAN (1-173): 7.13e-57: 177: 100.00		MYH9_HUMAN (1-817): 0: 992: 32.86
+	Hs
		214439 TP4A3_HUMAN (1-173): 7.13e-57: 177: 100.00		MYO1B_HUMAN (10-787): 0: 707: 47.73
+	Hs
		214543 PTEN_HUMAN (5-163): 2.34e-41: 144: 18.86		MYO1B_HUMAN (10-787): 0: 707: 47.73
+	Hs
		260550 TP4A3_HUMAN (1-173): 7.13e-57: 177: 100.00		MYO1E_HUMAN (10-722): 0: 569: 42.54
+	Sp
		1350785 FLP1_SCHPO (3-160): 6.58e-39: 140: 21.97		MYO1_SCHPO (10-1000): 5.45e-165: 518: 34.99
+	Hs
		64598 TENS2_HUMAN (4-168): 8.07e-39: 142: 13.74		MYH7B_HUMAN (683-998): 1.36e-14: 81.1: 11.32