HitPredict

Interactor 1: TP4A3 (O75365)
Protein tyrosine phosphatase type IVA 3 (EC 3.1.3.48) (PRL-R) (Protein-tyrosine phosphatase 4a3) (Protein-tyrosine phosphatase of regenerating liver 3) (PRL-3)
Gene: PTP4A3

Interactor 2: TP4A2 (Q12974)
Protein tyrosine phosphatase type IVA 2 (EC 3.1.3.48) (HU-PP-1) (OV-1) (PTP(CAAXII)) (Protein-tyrosine phosphatase 4a2) (Protein-tyrosine phosphatase of regenerating liver 2) (PRL-2)
Gene: PTP4A2

Species: Homo sapiens

Source: intact

Category: High-throughput

Confidence: High

Method score Annotation score Interaction score
0.81 1.00 0.903

The method score is based on:

Property Details
Experiments 28514442, 27432908, 28330616, 33961781
Identification Methods affinity chromatography technology, pull down, anti tag coimmunoprecipitation
Interaction Type physical association, association

The annotation score is based on:

Property Details
Interacting Pfam domains Y_phosphatase~Y_phosphatase
Common GO terms GO:0004725 - protein tyrosine phosphatase activity
GO:0004727 - prenylated protein tyrosine phosphatase activity
GO:0005634 - nucleus
GO:0005737 - cytoplasm
GO:0005769 - early endosome
and 2 others

more...
Homologous interactions 16

Homologous interactions

Color coding for hit scores

1 173
Hs

1 167
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Last updated: 15 Jul 2024