HitPredict

Interactor 1: H2AY (O75367)
Core histone macro-H2A.1 (Histone macroH2A1) (mH2A1) (Histone H2A.y) (H2A/y) (Medulloblastoma antigen MU-MB-50.205)
Gene: MACROH2A1

Interactor 2: LMNA (P02545)
Prelamin-A/C [Cleaved into: Lamin-A/C (70 kDa lamin) (Renal carcinoma antigen NY-REN-32)]
Gene: LMNA

Species: Homo sapiens

Source: biogrid

Category: Small-scale

Confidence: High

Method score	Annotation score	Interaction score
0.56	0.60	0.584

Property	Details
Experiments	25948554, 22412018
Identification Methods	affinity chromatography technology, proximity labelling technology
Interaction Type	physical association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005634 - nucleus GO:0005654 - nucleoplasm
Homologous interactions	8

Homologous interactions

Color coding for hit scores

	1 369 Hs			1 664
+	Hs
		260752 H2AY_HUMAN (1-369): 6.49e-165: 467: 100.00		LMNB1_HUMAN (21-580): 5.16e-50: 185: 54.37
+	Hs
		595451 H2AW_HUMAN (1-368): 1.41e-145: 418: 66.04		LMNB1_HUMAN (21-580): 5.16e-50: 185: 54.37
+	Hs
		359625 H2AX_HUMAN (1-142): 1.07e-65: 206: 60.69		LMNA_HUMAN (1-664): 7.64e-79: 265: 100.00
+	Hs
		360118 H2A2B_HUMAN (1-125): 5.78e-65: 204: 64.06		LMNA_HUMAN (1-664): 7.64e-79: 265: 100.00
+	Hs
		359562 H2A1B_HUMAN (1-126): 1.27e-64: 203: 62.02		LMNA_HUMAN (1-664): 7.64e-79: 265: 100.00
+	Hs
		595376 H2A1J_HUMAN (1-125): 5.25e-65: 204: 62.50		LMNB1_HUMAN (21-580): 5.16e-50: 185: 54.37
+	Hs
		595247 H2A2C_HUMAN (1-125): 9.23e-64: 201: 63.28		LMNB1_HUMAN (21-580): 5.16e-50: 185: 54.37
+	Hs
		391510 H2A1B_HUMAN (1-126): 1.27e-64: 203: 62.02		VIME_HUMAN (27-389): 3.94e-31: 129: 28.93