HitPredict

Interactor 1: H2AY (O75367)
Core histone macro-H2A.1 (Histone macroH2A1) (mH2A1) (Histone H2A.y) (H2A/y) (Medulloblastoma antigen MU-MB-50.205)
Gene: MACROH2A1

Interactor 2: HMGN2 (P05204)
Non-histone chromosomal protein HMG-17 (High mobility group nucleosome-binding domain-containing protein 2)
Gene: HMGN2

Species: Homo sapiens

Source: intact

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.62	0.60	0.611

Property	Details
Experiments	28514442, 24981860
Identification Methods	affinity chromatography technology, anti tag coimmunoprecipitation
Interaction Type	physical association, association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0000785 - chromatin GO:0005634 - nucleus GO:0031492 - nucleosomal DNA binding
Homologous interactions	13

Homologous interactions

Color coding for hit scores

	1 369 Hs			1 90
+	Hs
		130208 H2AY_HUMAN (1-369): 6.49e-165: 467: 100.00		HMGN4_HUMAN (1-90): 7.94e-22: 82.9: 86.67
+	Hs
		398960 H2AW_HUMAN (1-368): 1.41e-145: 418: 66.04		HMGN2_HUMAN (1-90): 3.72e-31: 106: 100.00
+	Hs
		130282 H2AW_HUMAN (1-368): 1.41e-145: 418: 66.04		HMGN4_HUMAN (1-90): 7.94e-22: 82.9: 86.67
+	Hs
		398923 H2A1C_HUMAN (1-126): 5.97e-65: 204: 62.79		HMGN2_HUMAN (1-90): 3.72e-31: 106: 100.00
+	Hs
		398938 H2A1J_HUMAN (1-125): 5.25e-65: 204: 62.50		HMGN2_HUMAN (1-90): 3.72e-31: 106: 100.00
+	Hs
		391496 H2A1B_HUMAN (1-126): 1.27e-64: 203: 62.02		HMGN2_HUMAN (1-90): 3.72e-31: 106: 100.00
+	Hs
		398810 H2A1_HUMAN (1-126): 1.21e-64: 203: 62.02		HMGN2_HUMAN (1-90): 3.72e-31: 106: 100.00
+	Hs
		398895 H2A2A_HUMAN (1-126): 8.18e-65: 203: 63.57		HMGN2_HUMAN (1-90): 3.72e-31: 106: 100.00
+	Hs
		398933 H2A1H_HUMAN (1-125): 1.07e-64: 203: 62.50		HMGN2_HUMAN (1-90): 3.72e-31: 106: 100.00
+	Hs
		130258 H2A2B_HUMAN (1-125): 5.78e-65: 204: 64.06		HMGN4_HUMAN (1-90): 7.94e-22: 82.9: 86.67
+	Hs
		130269 H2A1J_HUMAN (1-125): 5.25e-65: 204: 62.50		HMGN4_HUMAN (1-90): 7.94e-22: 82.9: 86.67
+	Hs
		130220 H2A1_HUMAN (1-126): 1.21e-64: 203: 62.02		HMGN4_HUMAN (1-90): 7.94e-22: 82.9: 86.67
+	Hs
		130250 H2A2C_HUMAN (1-125): 9.23e-64: 201: 63.28		HMGN4_HUMAN (1-90): 7.94e-22: 82.9: 86.67