HitPredict

Interactor 1: H2AY (O75367)
Core histone macro-H2A.1 (Histone macroH2A1) (mH2A1) (Histone H2A.y) (H2A/y) (Medulloblastoma antigen MU-MB-50.205)
Gene: MACROH2A1

Interactor 2: NPM (P06748)
Nucleophosmin (NPM) (Nucleolar phosphoprotein B23) (Nucleolar protein NO38) (Numatrin)
Gene: NPM1

Species: Homo sapiens

Source: intact

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.47	0.60	0.536

Property	Details
Experiments	33961781
Identification Methods	affinity chromatography technology, anti tag coimmunoprecipitation
Interaction Type	physical association, association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005634 - nucleus GO:0005654 - nucleoplasm GO:0005730 - nucleolus GO:0006281 - DNA repair GO:0006334 - nucleosome assembly and 1 others more... GO:0019901 - protein kinase binding
Homologous interactions	8

Homologous interactions

Color coding for hit scores

	1 369 Hs			1 294
+	Hs
		418739 H2AW_HUMAN (1-368): 1.41e-145: 418: 66.04		NPM_HUMAN (1-294): 1.47e-143: 407: 100.00
+	Hs
		417903 H2AX_HUMAN (1-142): 1.07e-65: 206: 60.69		NPM_HUMAN (1-294): 1.47e-143: 407: 100.00
+	Hs
		418565 H2A1A_HUMAN (1-128): 2.11e-65: 205: 61.83		NPM_HUMAN (1-294): 1.47e-143: 407: 100.00
+	Hs
		391502 H2A1B_HUMAN (1-126): 1.27e-64: 203: 62.02		NPM_HUMAN (1-294): 1.47e-143: 407: 100.00
+	Hs
		418322 H2A2C_HUMAN (1-125): 9.23e-64: 201: 63.28		NPM_HUMAN (1-294): 1.47e-143: 407: 100.00
+	Hs
		271252 H2AX_HUMAN (1-142): 1.07e-65: 206: 60.69		NPM3_HUMAN (10-119): 6.13e-58: 185: 43.75
+	Hs
		271355 H2A2B_HUMAN (1-125): 5.78e-65: 204: 64.06		NPM3_HUMAN (10-119): 6.13e-58: 185: 43.75
+	Hs
		271251 H2A1_HUMAN (1-126): 1.21e-64: 203: 62.02		NPM3_HUMAN (10-119): 6.13e-58: 185: 43.75