HitPredict

Interactor 1: H2AY (O75367)
Core histone macro-H2A.1 (Histone macroH2A1) (mH2A1) (Histone H2A.y) (H2A/y) (Medulloblastoma antigen MU-MB-50.205)
Gene: MACROH2A1

Interactor 2: ROA1 (P09651)
Heterogeneous nuclear ribonucleoprotein A1 (hnRNP A1) (Helix-destabilizing protein) (Single-strand RNA-binding protein) (hnRNP core protein A1) [Cleaved into: Heterogeneous nuclear ribonucleoprotein A1, N-terminally processed]
Gene: HNRNPA1

Species: Homo sapiens

Source: biogrid

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.38	0.60	0.479

Property	Details
Experiments	34349018
Identification Methods	cross-linking study
Interaction Type	physical association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0003677 - DNA binding GO:0005634 - nucleus GO:0005654 - nucleoplasm GO:0070062 - extracellular exosome
Homologous interactions	20

Homologous interactions (Top 20)

Color coding for hit scores

	1 369 Hs			1 372
+	Hs
		260756 H2AY_HUMAN (1-369): 6.49e-165: 467: 100.00		ROA2_HUMAN (1-339): 4.42e-56: 188: 59.00
+	Hs
		453126 H2AX_HUMAN (1-142): 1.07e-65: 206: 60.69		ROA1_HUMAN (1-372): 3.69e-61: 202: 100.00
+	Hs
		391515 H2A1B_HUMAN (1-126): 1.27e-64: 203: 62.02		ROA1_HUMAN (1-372): 3.69e-61: 202: 100.00
+	Hs
		161956 H2AX_HUMAN (1-142): 1.07e-65: 206: 60.69		HNRDL_HUMAN (2-283): 5.5e-56: 190: 32.41
+	Hs
		555293 H2AX_HUMAN (1-142): 1.07e-65: 206: 60.69		ROA2_HUMAN (1-339): 4.42e-56: 188: 59.00
+	Hs
		391548 H2A1B_HUMAN (1-126): 1.27e-64: 203: 62.02		ROA2_HUMAN (1-339): 4.42e-56: 188: 59.00
+	Hs
		555618 H2AX_HUMAN (1-142): 1.07e-65: 206: 60.69		ROAA_HUMAN (6-184): 1.25e-35: 134: 39.44
+	Hs
		391862 H2A1B_HUMAN (1-126): 1.27e-64: 203: 62.02		ROAA_HUMAN (6-184): 1.25e-35: 134: 39.44
+	Hs
		555437 H2AX_HUMAN (1-142): 1.07e-65: 206: 60.69		ELAV2_HUMAN (1-186): 1.4e-22: 99.5: 14.98
+	Hs
		555455 H2AX_HUMAN (1-142): 1.07e-65: 206: 60.69		HNRPD_HUMAN (2-101): 4.8e-18: 86.4: 31.00
+	Hs
		1048189 H2A1A_HUMAN (1-128): 2.11e-65: 205: 61.83		HNRPD_HUMAN (2-101): 4.8e-18: 86.4: 31.00
+	Hs
		1048135 H2A2B_HUMAN (1-125): 5.78e-65: 204: 64.06		HNRPD_HUMAN (2-101): 4.8e-18: 86.4: 31.00
+	Hs
		1048169 H2A1C_HUMAN (1-126): 5.97e-65: 204: 62.79		HNRPD_HUMAN (2-101): 4.8e-18: 86.4: 31.00
+	Hs
		1048200 H2A1J_HUMAN (1-125): 5.25e-65: 204: 62.50		HNRPD_HUMAN (2-101): 4.8e-18: 86.4: 31.00
+	Hs
		1048120 H2A3_HUMAN (1-126): 8.92e-65: 203: 62.79		HNRPD_HUMAN (2-101): 4.8e-18: 86.4: 31.00
+	Hs
		1048183 H2A1H_HUMAN (1-125): 1.07e-64: 203: 62.50		HNRPD_HUMAN (2-101): 4.8e-18: 86.4: 31.00
+	Hs
		391691 H2A1B_HUMAN (1-126): 1.27e-64: 203: 62.02		HNRPD_HUMAN (2-101): 4.8e-18: 86.4: 31.00
+	Hs
		594845 H2A1D_HUMAN (1-126): 1.88e-64: 203: 62.02		HNRPD_HUMAN (2-101): 4.8e-18: 86.4: 31.00
+	Hs
		555590 H2AX_HUMAN (1-142): 1.07e-65: 206: 60.69		MSI2H_HUMAN (2-91): 6.69e-16: 79.8: 35.56
+	Hs
		391681 H2A1B_HUMAN (1-126): 1.27e-64: 203: 62.02		PABP4_HUMAN (102-190): 3.52e-15: 79: 15.56