HitPredict

Interactor 1: H2AY (O75367)
Core histone macro-H2A.1 (Histone macroH2A1) (mH2A1) (Histone H2A.y) (H2A/y) (Medulloblastoma antigen MU-MB-50.205)
Gene: MACROH2A1

Interactor 2: HMGA1 (P17096)
High mobility group protein HMG-I/HMG-Y (HMG-I(Y)) (High mobility group AT-hook protein 1) (High mobility group protein A1) (High mobility group protein R)
Gene: HMGA1

Species: Homo sapiens

Source: intact

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.65	0.60	0.628

Property	Details
Experiments	33961781, 35271311
Identification Methods	affinity chromatography technology, anti tag coimmunoprecipitation
Interaction Type	physical association, association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0003677 - DNA binding GO:0005634 - nucleus GO:0005654 - nucleoplasm GO:0019899 - enzyme binding GO:0030527 - structural constituent of chromatin
Homologous interactions	8

Homologous interactions

Color coding for hit scores

	1 369 Hs			1 107
+	Hs
		565053 H2AW_HUMAN (1-368): 1.41e-145: 418: 66.04		HMGA1_HUMAN (1-107): 5.75e-40: 130: 100.00
+	Hs
		555282 H2AX_HUMAN (1-142): 1.07e-65: 206: 60.69		HMGA1_HUMAN (1-107): 5.75e-40: 130: 100.00
+	Hs
		564959 H2A2B_HUMAN (1-125): 5.78e-65: 204: 64.06		HMGA1_HUMAN (1-107): 5.75e-40: 130: 100.00
+	Hs
		564989 H2A1C_HUMAN (1-126): 5.97e-65: 204: 62.79		HMGA1_HUMAN (1-107): 5.75e-40: 130: 100.00
+	Hs
		391537 H2A1B_HUMAN (1-126): 1.27e-64: 203: 62.02		HMGA1_HUMAN (1-107): 5.75e-40: 130: 100.00
+	Hs
		470258 H2A1_HUMAN (1-126): 1.21e-64: 203: 62.02		HMGA1_HUMAN (1-107): 5.75e-40: 130: 100.00
+	Hs
		564939 H2A2A_HUMAN (1-126): 8.18e-65: 203: 63.57		HMGA1_HUMAN (1-107): 5.75e-40: 130: 100.00
+	Hs
		564997 H2A1H_HUMAN (1-125): 1.07e-64: 203: 62.50		HMGA1_HUMAN (1-107): 5.75e-40: 130: 100.00