HitPredict

Interactor 1: H2AY (O75367)
Core histone macro-H2A.1 (Histone macroH2A1) (mH2A1) (Histone H2A.y) (H2A/y) (Medulloblastoma antigen MU-MB-50.205)
Gene: MACROH2A1

Interactor 2: ROA2 (P22626)
Heterogeneous nuclear ribonucleoproteins A2/B1 (hnRNP A2/B1)
Gene: HNRNPA2B1

Species: Homo sapiens

Source: biogrid

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.38	0.60	0.479

Property	Details
Experiments	34349018
Identification Methods	cross-linking study
Interaction Type	physical association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0000122 - negative regulation of transcription by RNA polymerase II GO:0000781 - chromosome, telomeric region GO:0005634 - nucleus GO:0005654 - nucleoplasm GO:0070062 - extracellular exosome
Homologous interactions	20

Homologous interactions (Top 20)

Color coding for hit scores

	1 369 Hs			1 353
+	Hs
		260726 H2AY_HUMAN (1-369): 6.49e-165: 467: 100.00		ROA1_HUMAN (3-96): 6.48e-16: 79.8: 31.92
+	Hs
		161956 H2AX_HUMAN (1-142): 1.07e-65: 206: 60.69		HNRDL_HUMAN (12-292): 9.81e-66: 215: 33.45
+	Hs
		555293 H2AX_HUMAN (1-142): 1.07e-65: 206: 60.69		ROA2_HUMAN (1-353): 9.07e-61: 200: 100.00
+	Hs
		391548 H2A1B_HUMAN (1-126): 1.27e-64: 203: 62.02		ROA2_HUMAN (1-353): 9.07e-61: 200: 100.00
+	Hs
		555590 H2AX_HUMAN (1-142): 1.07e-65: 206: 60.69		MSI2H_HUMAN (1-341): 1.1e-55: 186: 27.57
+	Hs
		391681 H2A1B_HUMAN (1-126): 1.27e-64: 203: 62.02		PABP4_HUMAN (19-200): 1.59e-38: 146: 19.67
+	Hs
		516349 H2AX_HUMAN (1-142): 1.07e-65: 206: 60.69		PABP1_HUMAN (12-200): 2.75e-37: 143: 18.95
+	Hs
		470244 H2A1_HUMAN (1-126): 1.21e-64: 203: 62.02		PABP1_HUMAN (12-200): 2.75e-37: 143: 18.95
+	Hs
		555455 H2AX_HUMAN (1-142): 1.07e-65: 206: 60.69		HNRPD_HUMAN (22-191): 3.34e-37: 138: 41.77
+	Hs
		1048189 H2A1A_HUMAN (1-128): 2.11e-65: 205: 61.83		HNRPD_HUMAN (22-191): 3.34e-37: 138: 41.77
+	Hs
		1048135 H2A2B_HUMAN (1-125): 5.78e-65: 204: 64.06		HNRPD_HUMAN (22-191): 3.34e-37: 138: 41.77
+	Hs
		1048169 H2A1C_HUMAN (1-126): 5.97e-65: 204: 62.79		HNRPD_HUMAN (22-191): 3.34e-37: 138: 41.77
+	Hs
		1048200 H2A1J_HUMAN (1-125): 5.25e-65: 204: 62.50		HNRPD_HUMAN (22-191): 3.34e-37: 138: 41.77
+	Hs
		1048105 H2A2A_HUMAN (1-126): 8.18e-65: 203: 63.57		HNRPD_HUMAN (22-191): 3.34e-37: 138: 41.77
+	Hs
		1048120 H2A3_HUMAN (1-126): 8.92e-65: 203: 62.79		HNRPD_HUMAN (22-191): 3.34e-37: 138: 41.77
+	Hs
		1048183 H2A1H_HUMAN (1-125): 1.07e-64: 203: 62.50		HNRPD_HUMAN (22-191): 3.34e-37: 138: 41.77
+	Hs
		391691 H2A1B_HUMAN (1-126): 1.27e-64: 203: 62.02		HNRPD_HUMAN (22-191): 3.34e-37: 138: 41.77
+	Hs
		594845 H2A1D_HUMAN (1-126): 1.88e-64: 203: 62.02		HNRPD_HUMAN (22-191): 3.34e-37: 138: 41.77
+	Hs
		453126 H2AX_HUMAN (1-142): 1.07e-65: 206: 60.69		ROA1_HUMAN (3-96): 6.48e-16: 79.8: 31.92
+	Hs
		391515 H2A1B_HUMAN (1-126): 1.27e-64: 203: 62.02		ROA1_HUMAN (3-96): 6.48e-16: 79.8: 31.92