HitPredict

Interactor 1: H2AY (O75367)
Core histone macro-H2A.1 (Histone macroH2A1) (mH2A1) (Histone H2A.y) (H2A/y) (Medulloblastoma antigen MU-MB-50.205)
Gene: MACROH2A1

Interactor 2: BRD2 (P25440)
Bromodomain-containing protein 2 (O27.1.1)
Gene: BRD2

Species: Homo sapiens

Source: biogrid

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.56	0.60	0.584

Property	Details
Experiments	31753913, 30554943
Identification Methods	affinity chromatography technology
Interaction Type	physical association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0000785 - chromatin GO:0005634 - nucleus GO:0005654 - nucleoplasm GO:0006334 - nucleosome assembly
Homologous interactions	20

Homologous interactions (Top 20)

Color coding for hit scores

	1 369 Hs			1 801
+	Hs
		631613 H2AW_HUMAN (1-368): 1.41e-145: 418: 66.04		BRD2_HUMAN (1-773): 1.09e-171: 517: 100.00
+	Hs
		260889 H2AY_HUMAN (1-369): 6.49e-165: 467: 100.00		BRD3_HUMAN (53-764): 4.91e-124: 390: 56.56
+	Hs
		1067170 H2AW_HUMAN (1-368): 1.41e-145: 418: 66.04		BRD3_HUMAN (53-764): 4.91e-124: 390: 56.56
+	Hs
		243698 H2AY_HUMAN (1-369): 6.49e-165: 467: 100.00		BRD4_HUMAN (26-765): 9.66e-99: 336: 45.89
+	Hs
		245038 H2AW_HUMAN (1-368): 1.41e-145: 418: 66.04		BRD4_HUMAN (26-765): 9.66e-99: 336: 45.89
+	Hs
		555299 H2AX_HUMAN (1-142): 1.07e-65: 206: 60.69		BRD2_HUMAN (1-773): 1.09e-171: 517: 100.00
+	Hs
		631492 H2A2B_HUMAN (1-125): 5.78e-65: 204: 64.06		BRD2_HUMAN (1-773): 1.09e-171: 517: 100.00
+	Hs
		555470 H2AX_HUMAN (1-142): 1.07e-65: 206: 60.69		BRD3_HUMAN (53-764): 4.91e-124: 390: 56.56
+	Hs
		1067038 H2A2B_HUMAN (1-125): 5.78e-65: 204: 64.06		BRD3_HUMAN (53-764): 4.91e-124: 390: 56.56
+	Hs
		260921 H2AY_HUMAN (1-369): 6.49e-165: 467: 100.00		PB1_HUMAN (306-773): 2.79e-18: 92.6: 12.33
+	Hs
		244634 H2A2B_HUMAN (1-125): 5.78e-65: 204: 64.06		BRD4_HUMAN (26-765): 9.66e-99: 336: 45.89
+	Hs
		244848 H2A1J_HUMAN (1-125): 5.25e-65: 204: 62.50		BRD4_HUMAN (26-765): 9.66e-99: 336: 45.89
+	Hs
		555430 H2AX_HUMAN (1-142): 1.07e-65: 206: 60.69		EP300_HUMAN (31-183): 5.52e-39: 159: 30.72
+	Hs
		998866 H2A2B_HUMAN (1-125): 5.78e-65: 204: 64.06		EP300_HUMAN (31-183): 5.52e-39: 159: 30.72
+	Hs
		555570 H2AX_HUMAN (1-142): 1.07e-65: 206: 60.69		KAT2B_HUMAN (293-452): 1.59e-31: 134: 25.00
+	Hs
		555569 H2AX_HUMAN (1-142): 1.07e-65: 206: 60.69		KAT2A_HUMAN (293-452): 5.67e-30: 129: 24.38
+	Hs
		319113 H2AX_HUMAN (1-142): 1.07e-65: 206: 60.69		BRD1_HUMAN (54-330): 3.85e-29: 127: 17.79
+	Hs
		1300654 H2A1A_HUMAN (1-128): 2.11e-65: 205: 61.83		BRD7_HUMAN (25-338): 4.42e-29: 125: 17.13
+	Hs
		555661 H2AX_HUMAN (1-142): 1.07e-65: 206: 60.69		BAZ1A_HUMAN (49-197): 1.07e-22: 106: 21.94
+	Hs
		555528 H2AX_HUMAN (1-142): 1.07e-65: 206: 60.69		PB1_HUMAN (306-773): 2.79e-18: 92.6: 12.33