HitPredict

Interactor 1: H2AY (O75367)
Core histone macro-H2A.1 (Histone macroH2A1) (mH2A1) (Histone H2A.y) (H2A/y) (Medulloblastoma antigen MU-MB-50.205)
Gene: MACROH2A1

Interactor 2: RFA1 (P27694)
Replication protein A 70 kDa DNA-binding subunit (RP-A p70) (Replication factor A protein 1) (RF-A protein 1) (Single-stranded DNA-binding protein) [Cleaved into: Replication protein A 70 kDa DNA-binding subunit, N-terminally processed]
Gene: RPA1

Species: Homo sapiens

Source: biogrid

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.38	0.60	0.479

Property	Details
Experiments	37827155
Identification Methods	proximity labelling technology
Interaction Type	physical association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0000781 - chromosome, telomeric region GO:0005634 - nucleus GO:0005654 - nucleoplasm GO:0006281 - DNA repair GO:0090734 - site of DNA damage
Homologous interactions	8

Homologous interactions

Color coding for hit scores

	1 369 Hs			1 616
+	Hs
		652467 H2AW_HUMAN (1-368): 1.41e-145: 418: 66.04		RFA1_HUMAN (1-616): 0: 781: 100.00
+	Hs
		652082 MACD1_HUMAN (172-363): 9.08e-66: 213: 22.56		RFA1_HUMAN (1-616): 0: 781: 100.00
+	Hs
		555303 H2AX_HUMAN (1-142): 1.07e-65: 206: 60.69		RFA1_HUMAN (1-616): 0: 781: 100.00
+	Hs
		651615 H2A2B_HUMAN (1-125): 5.78e-65: 204: 64.06		RFA1_HUMAN (1-616): 0: 781: 100.00
+	Hs
		391559 H2A1B_HUMAN (1-126): 1.27e-64: 203: 62.02		RFA1_HUMAN (1-616): 0: 781: 100.00
+	Hs
		651357 PAR14_HUMAN (104-369): 1.72e-21: 98.3: 19.26		RFA1_HUMAN (1-616): 0: 781: 100.00
+	Sc
		392299 H2A2_YEAST (14-123): 1.54e-41: 144: 67.27		RFA1_YEAST (4-615): 0: 596: 31.69
+	Sc
		392055 H2A1_YEAST (14-123): 2.85e-41: 143: 67.27		RFA1_YEAST (4-615): 0: 596: 31.69