HitPredict

Interactor 1: H2AY (O75367)
Core histone macro-H2A.1 (Histone macroH2A1) (mH2A1) (Histone H2A.y) (H2A/y) (Medulloblastoma antigen MU-MB-50.205)
Gene: MACROH2A1

Interactor 2: NR2C2 (P49116)
Nuclear receptor subfamily 2 group C member 2 (Orphan nuclear receptor TAK1) (Orphan nuclear receptor TR4) (Testicular receptor 4)
Gene: NR2C2

Species: Homo sapiens

Source: biogrid

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.38	0.60	0.479

Property	Details
Experiments	30463901
Identification Methods	affinity chromatography technology
Interaction Type	physical association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0000122 - negative regulation of transcription by RNA polymerase II GO:0000785 - chromatin GO:0000977 - RNA polymerase II transcription regulatory region sequence-specific DNA binding GO:0005654 - nucleoplasm
Homologous interactions	9

Homologous interactions

Color coding for hit scores

	1 369 Hs			1 596
+	Hs
		555346 H2AX_HUMAN (1-142): 1.07e-65: 206: 60.69		NR2C2_HUMAN (1-596): 0: 527: 100.00
+	Hs
		824166 H2A2B_HUMAN (1-125): 5.78e-65: 204: 64.06		NR2C2_HUMAN (1-596): 0: 527: 100.00
+	Hs
		391596 H2A1B_HUMAN (1-126): 1.27e-64: 203: 62.02		NR2C2_HUMAN (1-596): 0: 527: 100.00
+	Hs
		824106 H2A2A_HUMAN (1-126): 8.18e-65: 203: 63.57		NR2C2_HUMAN (1-596): 0: 527: 100.00
+	Hs
		488028 H2AW_HUMAN (1-368): 1.41e-145: 418: 66.04		RARA_HUMAN (66-191): 1.29e-27: 118: 44.53
+	Hs
		1087013 H2A2C_HUMAN (1-125): 9.23e-64: 201: 63.28		Q58EY0_HUMAN (108-581): 3.61e-89: 285: 18.41
+	Hs
		488015 H2A1A_HUMAN (1-128): 2.11e-65: 205: 61.83		RARA_HUMAN (66-191): 1.29e-27: 118: 44.53
+	Hs
		487991 H2A2B_HUMAN (1-125): 5.78e-65: 204: 64.06		RARA_HUMAN (66-191): 1.29e-27: 118: 44.53
+	Hs
		488005 H2A1C_HUMAN (1-126): 5.97e-65: 204: 62.79		RARA_HUMAN (66-191): 1.29e-27: 118: 44.53