HitPredict

Interactor 1: H2AY (O75367)
Core histone macro-H2A.1 (Histone macroH2A1) (mH2A1) (Histone H2A.y) (H2A/y) (Medulloblastoma antigen MU-MB-50.205)
Gene: MACROH2A1

Interactor 2: WDR5 (P61964)
WD repeat-containing protein 5 (BMP2-induced 3-kb gene protein)
Gene: WDR5

Species: Homo sapiens

Source: biogrid

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.38	0.60	0.479

Property	Details
Experiments	33022573
Identification Methods	affinity chromatography technology
Interaction Type	physical association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0000122 - negative regulation of transcription by RNA polymerase II GO:0005634 - nucleus GO:0005654 - nucleoplasm GO:0045815 - transcription initiation-coupled chromatin remodeling
Homologous interactions	10

Homologous interactions

Color coding for hit scores

	1 369 Hs			1 334
+	Hs
		555386 H2AX_HUMAN (1-142): 1.07e-65: 206: 60.69		WDR5_HUMAN (1-334): 2.77e-131: 379: 100.00
+	Hs
		391631 H2A1B_HUMAN (1-126): 1.27e-64: 203: 62.02		WDR5_HUMAN (1-334): 2.77e-131: 379: 100.00
+	Hs
		1346958 H2AW_HUMAN (1-368): 1.41e-145: 418: 66.04		NLE1_HUMAN (197-332): 1.05e-32: 128: 22.54
+	Hs
		260970 H2AY_HUMAN (1-369): 6.49e-165: 467: 100.00		SNR40_HUMAN (248-333): 6.9e-13: 70.4: 25.29
+	Hs
		792998 H2A2A_HUMAN (1-126): 8.18e-65: 203: 63.57		LIS1_HUMAN (2-289): 1.55e-94: 288: 29.49
+	Hs
		903273 PAR14_HUMAN (104-369): 1.72e-21: 98.3: 19.26		WDR5_HUMAN (1-334): 2.77e-131: 379: 100.00
+	Hs
		245612 H2A2A_HUMAN (1-126): 8.18e-65: 203: 63.57		TBL1X_HUMAN (6-202): 8.72e-54: 187: 26.32
+	Hs
		470457 H2A1_HUMAN (1-126): 1.21e-64: 203: 62.02		DAW1_HUMAN (144-333): 8.06e-44: 157: 30.69
+	Hs
		594860 H2A1D_HUMAN (1-126): 1.88e-64: 203: 62.02		FBXW7_HUMAN (198-333): 4.06e-28: 116: 30.15
+	Hs
		1151367 H2A2A_HUMAN (1-126): 8.18e-65: 203: 63.57		SNR40_HUMAN (248-333): 6.9e-13: 70.4: 25.29