HitPredict

Interactor 1: H2AY (O75367)
Core histone macro-H2A.1 (Histone macroH2A1) (mH2A1) (Histone H2A.y) (H2A/y) (Medulloblastoma antigen MU-MB-50.205)
Gene: MACROH2A1

Interactor 2: RS27A (P62979)
Ubiquitin-ribosomal protein eS31 fusion protein (Ubiquitin carboxyl extension protein 80) [Cleaved into: Ubiquitin; Small ribosomal subunit protein eS31 (40S ribosomal protein S27a)]
Gene: RPS27A

Species: Homo sapiens

Source: biogrid

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.38	1.00	0.618

Property	Details
Experiments	34349018
Identification Methods	cross-linking study
Interaction Type	physical association

Property	Details
Interacting Pfam domains	Histone~ubiquitin
Common GO terms	GO:0005634 - nucleus GO:0005654 - nucleoplasm GO:0005730 - nucleolus GO:0070062 - extracellular exosome
Homologous interactions	18

Homologous interactions

Color coding for hit scores

	1 369 Hs			1 156
+	Hs
		924198 H2AW_HUMAN (1-368): 1.41e-145: 418: 66.04		RS27A_HUMAN (1-156): 3.55e-76: 225: 100.00
+	Rn
		70076 B1WC28_RAT (1-367): 7e-147: 421: 66.49		UBC_RAT (1-119): 1.57e-36: 134: 68.29
+	Hs
		555403 H2AX_HUMAN (1-142): 1.07e-65: 206: 60.69		RS27A_HUMAN (1-156): 3.55e-76: 225: 100.00
+	Hs
		391643 H2A1B_HUMAN (1-126): 1.27e-64: 203: 62.02		RS27A_HUMAN (1-156): 3.55e-76: 225: 100.00
+	Hs
		470331 H2A1_HUMAN (1-126): 1.21e-64: 203: 62.02		RS27A_HUMAN (1-156): 3.55e-76: 225: 100.00
+	Hs
		924034 H2A2A_HUMAN (1-126): 8.18e-65: 203: 63.57		RS27A_HUMAN (1-156): 3.55e-76: 225: 100.00
+	Hs
		924049 H2A3_HUMAN (1-126): 8.92e-65: 203: 62.79		RS27A_HUMAN (1-156): 3.55e-76: 225: 100.00
+	Hs
		555404 H2AX_HUMAN (1-142): 1.07e-65: 206: 60.69		RL40_HUMAN (1-125): 5.33e-44: 142: 64.80
+	Hs
		924374 H2A1C_HUMAN (1-126): 5.97e-65: 204: 62.79		RL40_HUMAN (1-125): 5.33e-44: 142: 64.80
+	Hs
		924397 H2A1J_HUMAN (1-125): 5.25e-65: 204: 62.50		RL40_HUMAN (1-125): 5.33e-44: 142: 64.80
+	Hs
		391644 H2A1B_HUMAN (1-126): 1.27e-64: 203: 62.02		RL40_HUMAN (1-125): 5.33e-44: 142: 64.80
+	Hs
		470332 H2A1_HUMAN (1-126): 1.21e-64: 203: 62.02		RL40_HUMAN (1-125): 5.33e-44: 142: 64.80
+	Hs
		924322 H2A2A_HUMAN (1-126): 8.18e-65: 203: 63.57		RL40_HUMAN (1-125): 5.33e-44: 142: 64.80
+	Hs
		924334 H2A3_HUMAN (1-126): 8.92e-65: 203: 62.79		RL40_HUMAN (1-125): 5.33e-44: 142: 64.80
+	Hs
		924387 H2A1H_HUMAN (1-125): 1.07e-64: 203: 62.50		RL40_HUMAN (1-125): 5.33e-44: 142: 64.80
+	Rn
		474085 H2A2A_RAT (1-126): 8.18e-65: 203: 63.57		UBC_RAT (1-119): 1.57e-36: 134: 68.29
+	Hs
		474911 H2AX_HUMAN (1-142): 1.07e-65: 206: 60.69		UBB_HUMAN (1-76): 6.65e-36: 125: 100.00
+	Sc
		392251 H2A2_YEAST (14-123): 1.54e-41: 144: 67.27		RL40A_YEAST (1-125): 2.07e-42: 139: 64.00