HitPredict

Interactor 1: H2AY (O75367)
Core histone macro-H2A.1 (Histone macroH2A1) (mH2A1) (Histone H2A.y) (H2A/y) (Medulloblastoma antigen MU-MB-50.205)
Gene: MACROH2A1

Interactor 2: XPC (Q01831)
DNA repair protein complementing XP-C cells (Xeroderma pigmentosum group C-complementing protein) (p125)
Gene: XPC

Species: Homo sapiens

Source: intact

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.73	0.60	0.662

Property	Details
Experiments	28514442, 33961781, 34591642
Identification Methods	affinity chromatography technology, anti tag coimmunoprecipitation
Interaction Type	physical association, association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0000785 - chromatin GO:0005634 - nucleus GO:0005654 - nucleoplasm GO:0005730 - nucleolus GO:0006281 - DNA repair and 1 others more... GO:0090734 - site of DNA damage
Homologous interactions	8

Homologous interactions

Color coding for hit scores

	1 369 Hs			1 940
+	Hs
		967092 H2AW_HUMAN (1-368): 1.41e-145: 418: 66.04		XPC_HUMAN (1-940): 0: 1158: 100.00
+	Hs
		967072 MACD1_HUMAN (172-363): 9.08e-66: 213: 22.56		XPC_HUMAN (1-940): 0: 1158: 100.00
+	Hs
		555418 H2AX_HUMAN (1-142): 1.07e-65: 206: 60.69		XPC_HUMAN (1-940): 0: 1158: 100.00
+	Hs
		967049 H2A2B_HUMAN (1-125): 5.78e-65: 204: 64.06		XPC_HUMAN (1-940): 0: 1158: 100.00
+	Hs
		391659 H2A1B_HUMAN (1-126): 1.27e-64: 203: 62.02		XPC_HUMAN (1-940): 0: 1158: 100.00
+	Hs
		470354 H2A1_HUMAN (1-126): 1.21e-64: 203: 62.02		XPC_HUMAN (1-940): 0: 1158: 100.00
+	Hs
		967041 H2A2A_HUMAN (1-126): 8.18e-65: 203: 63.57		XPC_HUMAN (1-940): 0: 1158: 100.00
+	Hs
		967036 H2A2C_HUMAN (1-125): 9.23e-64: 201: 63.28		XPC_HUMAN (1-940): 0: 1158: 100.00