HitPredict

Interactor 1: H2AY (O75367)
Core histone macro-H2A.1 (Histone macroH2A1) (mH2A1) (Histone H2A.y) (H2A/y) (Medulloblastoma antigen MU-MB-50.205)
Gene: MACROH2A1

Interactor 2: TIE2 (Q02763)
Angiopoietin-1 receptor (EC 2.7.10.1) (Endothelial tyrosine kinase) (Tunica interna endothelial cell kinase) (Tyrosine kinase with Ig and EGF homology domains-2) (Tyrosine-protein kinase receptor TEK) (Tyrosine-protein kinase receptor TIE-2) (hTIE2) (p140 TEK) (CD antigen CD202b)
Gene: TEK

Species: Homo sapiens

Source: intact

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.47	0.50	0.489

Property	Details
Experiments	35384245
Identification Methods	proximity labelling technology, proximity-dependent biotin identification
Interaction Type	physical association, association

Property	Details
Interacting Pfam domains	-
Common GO terms	-
Homologous interactions	6

Homologous interactions

Color coding for hit scores

	1 369 Hs			1 1124
+	Hs
		260766 H2AY_HUMAN (1-369): 6.49e-165: 467: 100.00		UFO_HUMAN (330-1106): 3.07e-162: 505: 23.47
+	Hs
		260755 H2AY_HUMAN (1-369): 6.49e-165: 467: 100.00		FGFR3_HUMAN (350-1118): 1.89e-157: 490: 24.44
+	Hs
		260723 H2AY_HUMAN (1-369): 6.49e-165: 467: 100.00		ROS1_HUMAN (448-1123): 1.09e-128: 437: 24.41
+	Hs
		665321 MACD1_HUMAN (172-363): 9.08e-66: 213: 22.56		EPHA2_HUMAN (442-1123): 7.37e-153: 483: 22.10
+	Hs
		260861 H2AY_HUMAN (1-369): 6.49e-165: 467: 100.00		MERTK_HUMAN (350-632): 2.4e-17: 89.7: 16.89
+	Hs
		1018366 H2AW_HUMAN (1-368): 1.41e-145: 418: 66.04		MERTK_HUMAN (350-632): 2.4e-17: 89.7: 16.89