HitPredict

Interactor 1: H2AY (O75367)
Core histone macro-H2A.1 (Histone macroH2A1) (mH2A1) (Histone H2A.y) (H2A/y) (Medulloblastoma antigen MU-MB-50.205)
Gene: MACROH2A1

Interactor 2: PB1 (Q86U86)
Protein polybromo-1 (hPB1) (BRG1-associated factor 180) (BAF180) (Polybromo-1D)
Gene: PBRM1

Species: Homo sapiens

Source: biogrid

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.38	1.00	0.618

Property	Details
Experiments	28242625
Identification Methods	affinity chromatography technology
Interaction Type	physical association

Property	Details
Interacting Pfam domains	BAH~Histone
Common GO terms	GO:0000228 - nuclear chromosome GO:0000785 - chromatin GO:0003677 - DNA binding GO:0005634 - nucleus GO:0005654 - nucleoplasm
Homologous interactions	20

Homologous interactions (Top 20)

Color coding for hit scores

	1 369 Hs			1 1689
+	Hs
		555528 H2AX_HUMAN (1-142): 1.07e-65: 206: 60.69		PB1_HUMAN (1-1689): 0: 1223: 100.00
+	Hs
		391768 H2A1B_HUMAN (1-126): 1.27e-64: 203: 62.02		PB1_HUMAN (1-1689): 0: 1223: 100.00
+	Hs
		1087035 H2A2C_HUMAN (1-125): 9.23e-64: 201: 63.28		PB1_HUMAN (1-1689): 0: 1223: 100.00
+	Hs
		260889 H2AY_HUMAN (1-369): 6.49e-165: 467: 100.00		BRD3_HUMAN (358-959): 6.75e-48: 186: 12.76
+	Hs
		1067170 H2AW_HUMAN (1-368): 1.41e-145: 418: 66.04		BRD3_HUMAN (358-959): 6.75e-48: 186: 12.76
+	Hs
		260758 H2AY_HUMAN (1-369): 6.49e-165: 467: 100.00		BRD2_HUMAN (2-169): 7.14e-20: 98.6: 15.29
+	Hs
		260802 H2AY_HUMAN (1-369): 6.49e-165: 467: 100.00		SMCA4_HUMAN (764-881): 7.55e-11: 69.5: 23.58
+	Hs
		631613 H2AW_HUMAN (1-368): 1.41e-145: 418: 66.04		BRD2_HUMAN (2-169): 7.14e-20: 98.6: 15.29
+	Hs
		641230 H2A2C_HUMAN (1-125): 9.23e-64: 201: 63.28		DNMT1_HUMAN (301-1361): 1.76e-75: 280: 12.20
+	Xl
		420791 H2A1_XENLA (1-126): 5.99e-64: 201: 62.79		P79922_XENLA (585-1361): 7.33e-72: 268: 13.31
+	Xl
		945507 H2AX_XENLA (1-135): 6.26e-64: 201: 57.25		P79922_XENLA (585-1361): 7.33e-72: 268: 13.31
+	Hs
		555470 H2AX_HUMAN (1-142): 1.07e-65: 206: 60.69		BRD3_HUMAN (358-959): 6.75e-48: 186: 12.76
+	Hs
		1067038 H2A2B_HUMAN (1-125): 5.78e-65: 204: 64.06		BRD3_HUMAN (358-959): 6.75e-48: 186: 12.76
+	Hs
		1067005 H2A2A_HUMAN (1-126): 8.18e-65: 203: 63.57		BRD3_HUMAN (358-959): 6.75e-48: 186: 12.76
+	Hs
		1066979 H2A2C_HUMAN (1-125): 9.23e-64: 201: 63.28		BRD3_HUMAN (358-959): 6.75e-48: 186: 12.76
+	Hs
		555299 H2AX_HUMAN (1-142): 1.07e-65: 206: 60.69		BRD2_HUMAN (2-169): 7.14e-20: 98.6: 15.29
+	Hs
		631492 H2A2B_HUMAN (1-125): 5.78e-65: 204: 64.06		BRD2_HUMAN (2-169): 7.14e-20: 98.6: 15.29
+	Hs
		391554 H2A1B_HUMAN (1-126): 1.27e-64: 203: 62.02		BRD2_HUMAN (2-169): 7.14e-20: 98.6: 15.29
+	Hs
		555359 H2AX_HUMAN (1-142): 1.07e-65: 206: 60.69		SMCA4_HUMAN (764-881): 7.55e-11: 69.5: 23.58
+	Hs
		555358 H2AX_HUMAN (1-142): 1.07e-65: 206: 60.69		SMCA2_HUMAN (794-881): 2.15e-09: 64.9: 26.09