HitPredict

Interactor 1: H2AY (O75367)
Core histone macro-H2A.1 (Histone macroH2A1) (mH2A1) (Histone H2A.y) (H2A/y) (Medulloblastoma antigen MU-MB-50.205)
Gene: MACROH2A1

Interactor 2: WDR76 (Q9H967)
WD repeat-containing protein 76
Gene: WDR76

Species: Homo sapiens

Source: biogrid

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.56	0.60	0.584

Property	Details
Experiments	27248496, 31353912
Identification Methods	affinity chromatography technology
Interaction Type	physical association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0003677 - DNA binding GO:0005634 - nucleus GO:0019899 - enzyme binding GO:0090734 - site of DNA damage
Homologous interactions	20

Homologous interactions (Top 20)

Color coding for hit scores

	1 369 Hs			1 626
+	Hs
		1334034 H2AW_HUMAN (1-368): 1.41e-145: 418: 66.04		WDR76_HUMAN (1-626): 1.19e-151: 453: 100.00
+	Hs
		260946 H2AY_HUMAN (1-369): 6.49e-165: 467: 100.00		COP1_HUMAN (154-619): 7.6e-71: 245: 14.96
+	Hs
		1274390 H2A1C_HUMAN (1-126): 5.97e-65: 204: 62.79		WDR76_HUMAN (1-626): 1.19e-151: 453: 100.00
+	Hs
		1151382 H2A2A_HUMAN (1-126): 8.18e-65: 203: 63.57		WDR76_HUMAN (1-626): 1.19e-151: 453: 100.00
+	Hs
		391908 H2A1B_HUMAN (1-126): 1.27e-64: 203: 62.02		WDR76_HUMAN (1-626): 1.19e-151: 453: 100.00
+	Hs
		1346958 H2AW_HUMAN (1-368): 1.41e-145: 418: 66.04		NLE1_HUMAN (181-575): 1.3e-63: 219: 12.70
+	Hs
		260822 H2AY_HUMAN (1-369): 6.49e-165: 467: 100.00		WDR5_HUMAN (435-622): 2.2e-42: 157: 12.23
+	Hs
		260970 H2AY_HUMAN (1-369): 6.49e-165: 467: 100.00		SNR40_HUMAN (440-625): 1.07e-33: 134: 11.83
+	Hs
		470457 H2A1_HUMAN (1-126): 1.21e-64: 203: 62.02		DAW1_HUMAN (132-575): 2.76e-78: 256: 14.87
+	Hs
		391818 H2A1B_HUMAN (1-126): 1.27e-64: 203: 62.02		DDB2_HUMAN (201-625): 1.38e-70: 236: 21.51
+	Hs
		1087068 H2A2C_HUMAN (1-125): 9.23e-64: 201: 63.28		DDB2_HUMAN (201-625): 1.38e-70: 236: 21.51
+	Hs
		594860 H2A1D_HUMAN (1-126): 1.88e-64: 203: 62.02		FBXW7_HUMAN (180-616): 3.15e-66: 231: 11.79
+	Sc
		392616 H2A2_YEAST (14-123): 1.54e-41: 144: 67.27		CMR1_YEAST (159-623): 1.38e-74: 249: 23.50
+	Hs
		792998 H2A2A_HUMAN (1-126): 8.18e-65: 203: 63.57		LIS1_HUMAN (118-478): 6.33e-51: 183: 9.73
+	Hs
		555386 H2AX_HUMAN (1-142): 1.07e-65: 206: 60.69		WDR5_HUMAN (435-622): 2.2e-42: 157: 12.23
+	Hs
		391631 H2A1B_HUMAN (1-126): 1.27e-64: 203: 62.02		WDR5_HUMAN (435-622): 2.2e-42: 157: 12.23
+	Hs
		245612 H2A2A_HUMAN (1-126): 8.18e-65: 203: 63.57		TBL1X_HUMAN (248-479): 3.7e-39: 153: 13.67
+	Hs
		1151367 H2A2A_HUMAN (1-126): 8.18e-65: 203: 63.57		SNR40_HUMAN (440-625): 1.07e-33: 134: 11.83
+	Hs
		997767 H2A2A_HUMAN (1-126): 8.18e-65: 203: 63.57		RBBP4_HUMAN (233-477): 2.84e-19: 92.6: 14.55
+	Hs
		997743 H2A2C_HUMAN (1-125): 9.23e-64: 201: 63.28		RBBP4_HUMAN (233-477): 2.84e-19: 92.6: 14.55