HitPredict

Interactor 1: H2AY (O75367)
Core histone macro-H2A.1 (Histone macroH2A1) (mH2A1) (Histone H2A.y) (H2A/y) (Medulloblastoma antigen MU-MB-50.205)
Gene: MACROH2A1

Interactor 2: HECD1 (Q9ULT8)
E3 ubiquitin-protein ligase HECTD1 (EC 2.3.2.26) (E3 ligase for inhibin receptor) (EULIR) (HECT domain-containing protein 1)
Gene: HECTD1

Species: Homo sapiens

Source: biogrid

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.38	0.50	0.437

Property	Details
Experiments	35915203
Identification Methods	affinity chromatography technology
Interaction Type	physical association

Property	Details
Interacting Pfam domains	-
Common GO terms	-
Homologous interactions	12

Homologous interactions

Color coding for hit scores

	1 369 Hs			1 2610
+	Hs
		1349694 H2AW_HUMAN (1-368): 1.41e-145: 418: 66.04		HECD1_HUMAN (1-2610): 0: 2419: 100.00
+	Hs
		261015 H2AY_HUMAN (1-369): 6.49e-165: 467: 100.00		SMUF1_HUMAN (2220-2607): 1.5e-116: 391: 19.70
+	Hs
		1327927 H2AW_HUMAN (1-368): 1.41e-145: 418: 66.04		WWP1_HUMAN (2328-2608): 5.47e-91: 321: 29.27
+	Hs
		303995 H2A1B_HUMAN (1-126): 1.27e-64: 203: 62.02		UBR5_HUMAN (1985-2609): 1.07e-116: 418: 16.94
+	Hs
		555605 H2AX_HUMAN (1-142): 1.07e-65: 206: 60.69		NED4L_HUMAN (2255-2608): 4.26e-117: 399: 21.67
+	Hs
		1299601 H2A1A_HUMAN (1-128): 2.11e-65: 205: 61.83		NED4L_HUMAN (2255-2608): 4.26e-117: 399: 21.67
+	Hs
		555651 H2AX_HUMAN (1-142): 1.07e-65: 206: 60.69		SMUF2_HUMAN (2235-2607): 4.78e-118: 395: 20.62
+	Hs
		125677 H2A1J_HUMAN (1-125): 5.25e-65: 204: 62.50		WWP2_HUMAN (2265-2608): 1.64e-107: 368: 24.86
+	Sc
		392126 H2A1_YEAST (14-123): 2.85e-41: 143: 67.27		RSP5_YEAST (2265-2608): 2.06e-105: 360: 20.86
+	Hs
		391698 H2A1B_HUMAN (1-126): 1.27e-64: 203: 62.02		TRIPC_HUMAN (5-1083): 4.48e-58: 225: 14.03
+	Hs
		1056622 H2AJ_HUMAN (1-125): 1.21e-63: 200: 62.50		TRIPC_HUMAN (5-1083): 4.48e-58: 225: 14.03
+	Hs
		391665 H2A1B_HUMAN (1-126): 1.27e-64: 203: 62.02		UBE3A_HUMAN (2406-2607): 5.17e-25: 116: 34.95