HitPredict

Interactor 1: FLNB (O75369)
Filamin-B (FLN-B) (ABP-278) (ABP-280 homolog) (Actin-binding-like protein) (Beta-filamin) (Filamin homolog 1) (Fh1) (Filamin-3) (Thyroid autoantigen) (Truncated actin-binding protein) (Truncated ABP)
Gene: FLNB

Interactor 2: PIAS1 (O75925)
E3 SUMO-protein ligase PIAS1 (EC 2.3.2.-) (DEAD/H box-binding protein 1) (E3 SUMO-protein transferase PIAS1) (Gu-binding protein) (GBP) (Protein inhibitor of activated STAT protein 1) (RNA helicase II-binding protein)
Gene: PIAS1

Species: Homo sapiens

Source: biogrid

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.38	0.60	0.479

Property	Details
Experiments	34537242
Identification Methods	affinity chromatography technology
Interaction Type	physical association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005737 - cytoplasm
Homologous interactions	6

Homologous interactions

Color coding for hit scores

	1 2602 Hs			1 651
+	Hs
		277933 FLNA_HUMAN (1-2602): 0: 2661: 69.59		PIAS1_HUMAN (1-651): 0: 874: 100.00
+	Hs
		278081 FLNC_HUMAN (6-2602): 0: 1470: 35.38		PIAS1_HUMAN (1-651): 0: 874: 100.00
+	Hs
		277910 ACTN1_HUMAN (5-364): 3.89e-117: 397: 27.15		PIAS1_HUMAN (1-651): 0: 874: 100.00
+	Hs
		278053 SPTB2_HUMAN (6-367): 4.86e-108: 389: 28.65		PIAS1_HUMAN (1-651): 0: 874: 100.00
+	Hs
		211442 ACTN4_HUMAN (12-364): 9.99e-114: 388: 26.58		PIAS1_HUMAN (1-651): 0: 874: 100.00
+	Hs
		521575 ACTN1_HUMAN (5-364): 3.89e-117: 397: 27.15		PIAS4_HUMAN (2-423): 0: 550: 51.42