HitPredict

Interactor 1: FLNB (O75369)
Filamin-B (FLN-B) (ABP-278) (ABP-280 homolog) (Actin-binding-like protein) (Beta-filamin) (Filamin homolog 1) (Fh1) (Filamin-3) (Thyroid autoantigen) (Truncated actin-binding protein) (Truncated ABP)
Gene: FLNB

Interactor 2: MYC (P01106)
Myc proto-oncogene protein (Class E basic helix-loop-helix protein 39) (bHLHe39) (Proto-oncogene c-Myc) (Transcription factor p64)
Gene: MYC

Species: Homo sapiens

Source: biogrid

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.68	0.60	0.640

Property	Details
Experiments	29467282, 35013218, 36424410
Identification Methods	affinity chromatography technology, proximity labelling technology
Interaction Type	physical association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005737 - cytoplasm
Homologous interactions	10

Homologous interactions

Color coding for hit scores

	1 2602 Hs			1 454
+	Hs
		345916 FLNA_HUMAN (1-2602): 0: 2661: 69.59		MYC_HUMAN (1-454): 1.73e-122: 366: 100.00
+	Hs
		347029 Q60FE5_HUMAN (1-2602): 0: 2660: 69.59		MYC_HUMAN (1-454): 1.73e-122: 366: 100.00
+	Hs
		379011 FLNA_HUMAN (1-2602): 0: 2661: 69.59		MYCN_HUMAN (12-451): 9.39e-59: 201: 33.40
+	Hs
		346774 FLNC_HUMAN (6-2602): 0: 1470: 35.38		MYC_HUMAN (1-454): 1.73e-122: 366: 100.00
+	Hs
		345805 ACTN1_HUMAN (5-364): 3.89e-117: 397: 27.15		MYC_HUMAN (1-454): 1.73e-122: 366: 100.00
+	Hs
		346544 SPTB2_HUMAN (6-367): 4.86e-108: 389: 28.65		MYC_HUMAN (1-454): 1.73e-122: 366: 100.00
+	Hs
		211453 ACTN4_HUMAN (12-364): 9.99e-114: 388: 26.58		MYC_HUMAN (1-454): 1.73e-122: 366: 100.00
+	Hs
		378964 ACTN1_HUMAN (5-364): 3.89e-117: 397: 27.15		MYCN_HUMAN (12-451): 9.39e-59: 201: 33.40
+	Hs
		963302 SPTB2_HUMAN (6-367): 4.86e-108: 389: 28.65		SRBP2_HUMAN (124-446): 8.64e-35: 139: 12.54
+	Hs
		348245 MACF1_HUMAN (16-239): 9.3e-35: 149: 40.69		MYC_HUMAN (1-454): 1.73e-122: 366: 100.00