HitPredict

Interactor 1: FLNB (O75369)
Filamin-B (FLN-B) (ABP-278) (ABP-280 homolog) (Actin-binding-like protein) (Beta-filamin) (Filamin homolog 1) (Fh1) (Filamin-3) (Thyroid autoantigen) (Truncated actin-binding protein) (Truncated ABP)
Gene: FLNB

Interactor 2: TAU (P10636)
Microtubule-associated protein tau (Neurofibrillary tangle protein) (Paired helical filament-tau) (PHF-tau)
Gene: MAPT

Species: Homo sapiens

Source: intact

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.33	0.60	0.445

Property	Details
Experiments	35063084
Identification Methods	anti tag coimmunoprecipitation
Interaction Type	association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0003723 - RNA binding GO:0003779 - actin binding GO:0005737 - cytoplasm GO:0005829 - cytosol GO:0005886 - plasma membrane
Homologous interactions	11

Homologous interactions

Color coding for hit scores

	1 2602 Hs			1 758
+	Hs
		261264 FLNB_HUMAN (1-2602): 0: 2855: 100.00		MDC1_HUMAN (2-755): 3.72e-28: 124: 8.57
+	Hs
		496293 FLNA_HUMAN (1-2602): 0: 2661: 69.59		TAU_HUMAN (1-758): 3.6e-89: 298: 100.00
+	Hs
		598120 FLNA_HUMAN (1-2602): 0: 2661: 69.59		MDC1_HUMAN (2-755): 3.72e-28: 124: 8.57
+	Hs
		497015 FLNC_HUMAN (6-2602): 0: 1470: 35.38		TAU_HUMAN (1-758): 3.6e-89: 298: 100.00
+	Hs
		496188 ACTN1_HUMAN (5-364): 3.89e-117: 397: 27.15		TAU_HUMAN (1-758): 3.6e-89: 298: 100.00
+	Hs
		496865 SPTB2_HUMAN (6-367): 4.86e-108: 389: 28.65		TAU_HUMAN (1-758): 3.6e-89: 298: 100.00
+	Hs
		211474 ACTN4_HUMAN (12-364): 9.99e-114: 388: 26.58		TAU_HUMAN (1-758): 3.6e-89: 298: 100.00
+	Rn
		582039 SPTN2_RAT (6-283): 4.23e-95: 347: 32.74		TAU_RAT (1-758): 4.86e-75: 260: 71.47
+	Rn
		94264 SPTN2_RAT (6-283): 4.23e-95: 347: 32.74		F1LST4_RAT (1-757): 8.59e-75: 260: 71.56
+	Hs
		503257 ACTN1_HUMAN (5-364): 3.89e-117: 397: 27.15		MTAP2_HUMAN (16-758): 2.28e-30: 131: 23.55
+	Dm
		1364755 FLNA_DROME (2172-2601): 1.6e-61: 237: 26.01		Q9VLS7_DROME (62-753): 1.93e-12: 73.2: 9.96