HitPredict

Interactor 1: FLNB (O75369)
Filamin-B (FLN-B) (ABP-278) (ABP-280 homolog) (Actin-binding-like protein) (Beta-filamin) (Filamin homolog 1) (Fh1) (Filamin-3) (Thyroid autoantigen) (Truncated actin-binding protein) (Truncated ABP)
Gene: FLNB

Interactor 2: CDK2 (P24941)
Cyclin-dependent kinase 2 (EC 2.7.11.22) (Cell division protein kinase 2) (p33 protein kinase)
Gene: CDK2

Species: Homo sapiens

Source: biogrid

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.38	0.60	0.479

Property	Details
Experiments	21319273
Identification Methods	affinity chromatography technology
Interaction Type	physical association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005737 - cytoplasm GO:0005829 - cytosol GO:0007165 - signal transduction
Homologous interactions	6

Homologous interactions

Color coding for hit scores

	1 2602 Hs			1 298
+	Hs
		597963 FLNA_HUMAN (1-2602): 0: 2661: 69.59		CDK2_HUMAN (1-298): 8.79e-167: 466: 100.00
+	Hs
		414734 FLNA_HUMAN (1-2602): 0: 2661: 69.59		CDK1_HUMAN (1-289): 7.44e-144: 408: 66.90
+	Hs
		625431 FLNC_HUMAN (6-2602): 0: 1470: 35.38		CDK2_HUMAN (1-298): 8.79e-167: 466: 100.00
+	Hs
		521469 ACTN1_HUMAN (5-364): 3.89e-117: 397: 27.15		CDK2_HUMAN (1-298): 8.79e-167: 466: 100.00
+	Hs
		625369 SPTB2_HUMAN (6-367): 4.86e-108: 389: 28.65		CDK2_HUMAN (1-298): 8.79e-167: 466: 100.00
+	Hs
		841168 SPTB2_HUMAN (6-367): 4.86e-108: 389: 28.65		CDK7_HUMAN (2-298): 9.81e-124: 359: 44.00