HitPredict

Interactor 1: FLNB (O75369)
Filamin-B (FLN-B) (ABP-278) (ABP-280 homolog) (Actin-binding-like protein) (Beta-filamin) (Filamin homolog 1) (Fh1) (Filamin-3) (Thyroid autoantigen) (Truncated actin-binding protein) (Truncated ABP)
Gene: FLNB

Interactor 2: P85A (P27986)
Phosphatidylinositol 3-kinase regulatory subunit alpha (PI3-kinase regulatory subunit alpha) (PI3K regulatory subunit alpha) (PtdIns-3-kinase regulatory subunit alpha) (Phosphatidylinositol 3-kinase 85 kDa regulatory subunit alpha) (PI3-kinase subunit p85-alpha) (PtdIns-3-kinase regulatory subunit p85-alpha)
Gene: PIK3R1

Species: Homo sapiens

Source: intact

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.38	0.60	0.479

Property	Details
Experiments	17474147
Identification Methods	peptide array
Interaction Type	physical association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005737 - cytoplasm GO:0005829 - cytosol GO:0005886 - plasma membrane GO:0016020 - membrane
Homologous interactions	7

Homologous interactions

Color coding for hit scores

	1 2602 Hs			1 724
+	Hs
		597968 FLNA_HUMAN (1-2602): 0: 2661: 69.59		P85A_HUMAN (1-724): 0: 596: 100.00
+	Hs
		598161 FLNA_HUMAN (1-2602): 0: 2661: 69.59		RHG21_HUMAN (78-531): 1.19e-59: 221: 13.46
+	Hs
		598221 FLNA_HUMAN (1-2602): 0: 2661: 69.59		RHG24_HUMAN (94-443): 7.45e-57: 208: 16.76
+	Hs
		655367 FLNC_HUMAN (6-2602): 0: 1470: 35.38		P85A_HUMAN (1-724): 0: 596: 100.00
+	Hs
		129277 SPTB2_HUMAN (6-367): 4.86e-108: 389: 28.65		P85B_HUMAN (4-719): 6.38e-162: 486: 57.24
+	Hs
		521574 ACTN1_HUMAN (5-364): 3.89e-117: 397: 27.15		RHG24_HUMAN (94-443): 7.45e-57: 208: 16.76
+	Hs
		211612 ACTN4_HUMAN (12-364): 9.99e-114: 388: 26.58		RHG24_HUMAN (94-443): 7.45e-57: 208: 16.76