HitPredict

Interactor 1: FLNB (O75369)
Filamin-B (FLN-B) (ABP-278) (ABP-280 homolog) (Actin-binding-like protein) (Beta-filamin) (Filamin homolog 1) (Fh1) (Filamin-3) (Thyroid autoantigen) (Truncated actin-binding protein) (Truncated ABP)
Gene: FLNB

Interactor 2: BMI1 (P35226)
Polycomb complex protein BMI-1 (Polycomb group RING finger protein 4) (RING finger protein 51)
Gene: BMI1

Species: Homo sapiens

Source: intact

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.33	0.60	0.445

Property	Details
Experiments	34316702
Identification Methods	anti bait coimmunoprecipitation
Interaction Type	association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005829 - cytosol
Homologous interactions	14

Homologous interactions

Color coding for hit scores

	1 2602 Hs			1 326
+	Hs
		597980 FLNA_HUMAN (1-2602): 0: 2661: 69.59		BMI1_HUMAN (1-326): 1.43e-153: 435: 100.00
+	Hs
		261314 FLNB_HUMAN (1-2602): 0: 2855: 100.00		RING2_HUMAN (7-227): 8.37e-50: 170: 16.61
+	Hs
		261297 FLNB_HUMAN (1-2602): 0: 2855: 100.00		DTX3_HUMAN (17-62): 3.98e-10: 62.2: 39.13
+	Hs
		598309 FLNA_HUMAN (1-2602): 0: 2661: 69.59		TRIM6_HUMAN (5-189): 2.83e-49: 173: 16.67
+	Hs
		598231 FLNA_HUMAN (1-2602): 0: 2661: 69.59		DTX3_HUMAN (17-62): 3.98e-10: 62.2: 39.13
+	Hs
		1052904 FLNC_HUMAN (6-2602): 0: 1470: 35.38		DTX3_HUMAN (17-62): 3.98e-10: 62.2: 39.13
+	Hs
		521481 ACTN1_HUMAN (5-364): 3.89e-117: 397: 27.15		BMI1_HUMAN (1-326): 1.43e-153: 435: 100.00
+	Hs
		717709 SPTB2_HUMAN (6-367): 4.86e-108: 389: 28.65		BMI1_HUMAN (1-326): 1.43e-153: 435: 100.00
+	Hs
		718318 MACF1_HUMAN (16-239): 9.3e-35: 149: 40.69		BMI1_HUMAN (1-326): 1.43e-153: 435: 100.00
+	Hs
		521464 ACTN1_HUMAN (5-364): 3.89e-117: 397: 27.15		RO52_HUMAN (5-198): 5.75e-52: 180: 18.78
+	Hs
		211495 ACTN4_HUMAN (12-364): 9.99e-114: 388: 26.58		RO52_HUMAN (5-198): 5.75e-52: 180: 18.78
+	Hs
		282506 ACTN1_HUMAN (5-364): 3.89e-117: 397: 27.15		RNF8_HUMAN (2-101): 3.38e-21: 95.7: 25.00
+	Hs
		282627 SPTB2_HUMAN (6-367): 4.86e-108: 389: 28.65		RNF8_HUMAN (2-101): 3.38e-21: 95.7: 25.00
+	Hs
		963368 SPTB2_HUMAN (6-367): 4.86e-108: 389: 28.65		DTX3_HUMAN (17-62): 3.98e-10: 62.2: 39.13