HitPredict

Interactor 1: FLNB (O75369)
Filamin-B (FLN-B) (ABP-278) (ABP-280 homolog) (Actin-binding-like protein) (Beta-filamin) (Filamin homolog 1) (Fh1) (Filamin-3) (Thyroid autoantigen) (Truncated actin-binding protein) (Truncated ABP)
Gene: FLNB

Interactor 2: YAP1 (P46937)
Transcriptional coactivator YAP1 (Yes-associated protein 1) (Protein yorkie homolog) (Yes-associated protein YAP65 homolog)
Gene: YAP1

Species: Homo sapiens

Source: biogrid

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.38	0.60	0.479

Property	Details
Experiments	31501420
Identification Methods	affinity chromatography technology
Interaction Type	physical association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005737 - cytoplasm GO:0005829 - cytosol GO:0016020 - membrane
Homologous interactions	15

Homologous interactions

Color coding for hit scores

	1 2602 Hs			1 504
+	Hs
		261331 FLNB_HUMAN (1-2602): 0: 2855: 100.00		SMUF2_HUMAN (99-504): 4.95e-107: 337: 19.19
+	Hs
		125152 FLNA_HUMAN (1-2602): 0: 2661: 69.59		WWP2_HUMAN (12-504): 8.56e-129: 397: 16.54
+	Hs
		598332 FLNA_HUMAN (1-2602): 0: 2661: 69.59		SMUF1_HUMAN (89-504): 7.79e-117: 363: 20.05
+	Hs
		598000 FLNA_HUMAN (1-2602): 0: 2661: 69.59		YAP1_HUMAN (1-504): 7.71e-118: 357: 100.00
+	Hs
		1052944 FLNC_HUMAN (6-2602): 0: 1470: 35.38		SMUF2_HUMAN (99-504): 4.95e-107: 337: 19.19
+	Hs
		1052900 FLNC_HUMAN (6-2602): 0: 1470: 35.38		KIBRA_HUMAN (167-309): 1.03e-35: 144: 27.27
+	Hs
		521619 ACTN1_HUMAN (5-364): 3.89e-117: 397: 27.15		SMUF1_HUMAN (89-504): 7.79e-117: 363: 20.05
+	Hs
		521493 ACTN1_HUMAN (5-364): 3.89e-117: 397: 27.15		YAP1_HUMAN (1-504): 7.71e-118: 357: 100.00
+	Hs
		963426 SPTB2_HUMAN (6-367): 4.86e-108: 389: 28.65		SMUF1_HUMAN (89-504): 7.79e-117: 363: 20.05
+	Hs
		808520 SPTB2_HUMAN (6-367): 4.86e-108: 389: 28.65		YAP1_HUMAN (1-504): 7.71e-118: 357: 100.00
+	Hs
		521598 ACTN1_HUMAN (5-364): 3.89e-117: 397: 27.15		MAGI1_HUMAN (69-305): 1.87e-39: 155: 18.32
+	Hs
		211645 ACTN4_HUMAN (12-364): 9.99e-114: 388: 26.58		MAGI1_HUMAN (69-305): 1.87e-39: 155: 18.32
+	Dm
		1364782 FLNA_DROME (2172-2601): 1.6e-61: 237: 26.01		Q9W325_DROME (254-504): 3.56e-53: 187: 11.42
+	Dm
		89901 FLNA_DROME (2172-2601): 1.6e-61: 237: 26.01		D5SHR3_DROME (258-504): 1.07e-52: 186: 11.60
+	Hs
		1350503 MACF1_HUMAN (16-239): 9.3e-35: 149: 40.69		HECW2_HUMAN (13-303): 1.56e-14: 79: 14.79