HitPredict

Interactor 1: FLNB (O75369)
Filamin-B (FLN-B) (ABP-278) (ABP-280 homolog) (Actin-binding-like protein) (Beta-filamin) (Filamin homolog 1) (Fh1) (Filamin-3) (Thyroid autoantigen) (Truncated actin-binding protein) (Truncated ABP)
Gene: FLNB

Interactor 2: PP1B (P62140)
Serine/threonine-protein phosphatase PP1-beta catalytic subunit (PP-1B) (PPP1CD) (EC 3.1.3.16) (EC 3.1.3.53)
Gene: PPP1CB

Species: Homo sapiens

Source: intact

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.47	0.60	0.536

Property	Details
Experiments	26496610
Identification Methods	affinity chromatography technology, anti tag coimmunoprecipitation
Interaction Type	physical association, association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005737 - cytoplasm GO:0005829 - cytosol GO:0005925 - focal adhesion GO:0070062 - extracellular exosome
Homologous interactions	8

Homologous interactions

Color coding for hit scores

	1 2602 Hs			1 327
+	Hs
		598043 FLNA_HUMAN (1-2602): 0: 2661: 69.59		PP1B_HUMAN (1-327): 0: 597: 100.00
+	Hs
		598042 FLNA_HUMAN (1-2602): 0: 2661: 69.59		PP1A_HUMAN (1-326): 0: 576: 88.79
+	Hs
		597988 FLNA_HUMAN (1-2602): 0: 2661: 69.59		PP1G_HUMAN (1-327): 0: 569: 86.89
+	Hs
		521519 ACTN1_HUMAN (5-364): 3.89e-117: 397: 27.15		PP1B_HUMAN (1-327): 0: 597: 100.00
+	Hs
		725638 ACTN2_HUMAN (5-364): 2.6e-116: 395: 26.61		PP1B_HUMAN (1-327): 0: 597: 100.00
+	Hs
		906417 SPTB2_HUMAN (6-367): 4.86e-108: 389: 28.65		PP1B_HUMAN (1-327): 0: 597: 100.00
+	Hs
		211552 ACTN4_HUMAN (12-364): 9.99e-114: 388: 26.58		PP1B_HUMAN (1-327): 0: 597: 100.00
+	Hs
		737749 SPTB2_HUMAN (6-367): 4.86e-108: 389: 28.65		PP1G_HUMAN (1-327): 0: 569: 86.89