HitPredict

Interactor 1: FLNB (O75369)
Filamin-B (FLN-B) (ABP-278) (ABP-280 homolog) (Actin-binding-like protein) (Beta-filamin) (Filamin homolog 1) (Fh1) (Filamin-3) (Thyroid autoantigen) (Truncated actin-binding protein) (Truncated ABP)
Gene: FLNB

Interactor 2: XIAP (P98170)
E3 ubiquitin-protein ligase XIAP (EC 2.3.2.27) (Baculoviral IAP repeat-containing protein 4) (IAP-like protein) (ILP) (hILP) (Inhibitor of apoptosis protein 3) (IAP-3) (hIAP-3) (hIAP3) (RING-type E3 ubiquitin transferase XIAP) (X-linked inhibitor of apoptosis protein) (X-linked IAP)
Gene: XIAP

Species: Homo sapiens

Source: biogrid

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.41	0.60	0.501

Property	Details
Experiments	36243803
Identification Methods	pull down
Interaction Type	direct interaction

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005737 - cytoplasm GO:0005829 - cytosol
Homologous interactions	8

Homologous interactions

Color coding for hit scores

	1 2602 Hs			1 497
+	Hs
		598066 FLNA_HUMAN (1-2602): 0: 2661: 69.59		XIAP_HUMAN (1-497): 0: 569: 100.00
+	Hs
		261254 FLNB_HUMAN (1-2602): 0: 2855: 100.00		BIRC3_HUMAN (150-394): 2.89e-41: 158: 23.94
+	Hs
		598100 FLNA_HUMAN (1-2602): 0: 2661: 69.59		BIRC3_HUMAN (150-394): 2.89e-41: 158: 23.94
+	Hs
		963315 SPTB2_HUMAN (6-367): 4.86e-108: 389: 28.65		BIRC3_HUMAN (150-394): 2.89e-41: 158: 23.94
+	Hs
		211575 ACTN4_HUMAN (12-364): 9.99e-114: 388: 26.58		BIRC3_HUMAN (150-394): 2.89e-41: 158: 23.94
+	Dr
		1186354 Q7SYD3_DANRE (5-364): 3.18e-119: 403: 27.42		MIB1_DANRE (311-496): 3.81e-21: 99.2: 13.55
+	Dr
		1103596 Q2YDR5_DANRE (5-364): 7.28e-118: 399: 25.81		MIB1_DANRE (311-496): 3.81e-21: 99.2: 13.55
+	Dr
		1186355 Q7SYE2_DANRE (5-365): 4.07e-117: 397: 28.11		MIB1_DANRE (311-496): 3.81e-21: 99.2: 13.55