HitPredict

Interactor 1: FLNB (O75369)
Filamin-B (FLN-B) (ABP-278) (ABP-280 homolog) (Actin-binding-like protein) (Beta-filamin) (Filamin homolog 1) (Fh1) (Filamin-3) (Thyroid autoantigen) (Truncated actin-binding protein) (Truncated ABP)
Gene: FLNB

Interactor 2: PKHA4 (Q9H4M7)
Pleckstrin homology domain-containing family A member 4 (PH domain-containing family A member 4) (Phosphoinositol 3-phosphate-binding protein 1) (PEPP-1)
Gene: PLEKHA4

Species: Homo sapiens

Source: biogrid

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.38	0.60	0.479

Property	Details
Experiments	31091453
Identification Methods	affinity chromatography technology
Interaction Type	physical association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005737 - cytoplasm GO:0005886 - plasma membrane
Homologous interactions	20

Homologous interactions (Top 20)

Color coding for hit scores

	1 2602 Hs			1 779
+	Hs
		598320 FLNA_HUMAN (1-2602): 0: 2661: 69.59		PKHA4_HUMAN (1-779): 4.1e-157: 477: 100.00
+	Hs
		598170 FLNA_HUMAN (1-2602): 0: 2661: 69.59		PKHA7_HUMAN (2-440): 4.98e-50: 192: 28.02
+	Hs
		596356 FLNA_HUMAN (1-2602): 0: 2661: 69.59		RASA1_HUMAN (72-437): 2.74e-44: 174: 11.32
+	Hs
		598184 FLNA_HUMAN (1-2602): 0: 2661: 69.59		MPRIP_HUMAN (2-499): 4.76e-44: 173: 16.57
+	Hs
		598161 FLNA_HUMAN (1-2602): 0: 2661: 69.59		RHG21_HUMAN (22-662): 1.96e-43: 172: 13.18
+	Hs
		598221 FLNA_HUMAN (1-2602): 0: 2661: 69.59		RHG24_HUMAN (55-181): 6.43e-27: 119: 25.93
+	Hs
		1052940 FLNC_HUMAN (6-2602): 0: 1470: 35.38		PKHA4_HUMAN (1-779): 4.1e-157: 477: 100.00
+	Hs
		521613 ACTN1_HUMAN (5-364): 3.89e-117: 397: 27.15		PKHA4_HUMAN (1-779): 4.1e-157: 477: 100.00
+	Hs
		725697 ACTN2_HUMAN (5-364): 2.6e-116: 395: 26.61		PKHA4_HUMAN (1-779): 4.1e-157: 477: 100.00
+	Hs
		963417 SPTB2_HUMAN (6-367): 4.86e-108: 389: 28.65		PKHA4_HUMAN (1-779): 4.1e-157: 477: 100.00
+	Hs
		211664 ACTN4_HUMAN (12-364): 9.99e-114: 388: 26.58		PKHA4_HUMAN (1-779): 4.1e-157: 477: 100.00
+	Hs
		521561 ACTN1_HUMAN (5-364): 3.89e-117: 397: 27.15		PKHA7_HUMAN (2-440): 4.98e-50: 192: 28.02
+	Hs
		57984 ACTN3_HUMAN (5-364): 1.21e-118: 402: 26.88		A2RRN7_HUMAN (57-428): 4.21e-47: 181: 12.44
+	Hs
		993303 ACTN3_HUMAN (5-364): 1.21e-118: 402: 26.88		CAPS1_HUMAN (11-428): 3.69e-46: 180: 11.26
+	Hs
		211598 ACTN4_HUMAN (12-364): 9.99e-114: 388: 26.58		PKHA7_HUMAN (2-440): 4.98e-50: 192: 28.02
+	Mm
		1143715 SPTB2_MOUSE (6-367): 4.85e-108: 389: 28.65		CNKR2_MOUSE (1-468): 7.51e-48: 185: 14.40
+	Hs
		211597 ACTN4_HUMAN (12-364): 9.99e-114: 388: 26.58		CYTSA_HUMAN (320-643): 3.92e-43: 171: 12.81
+	Hs
		963422 SPTB2_HUMAN (6-367): 4.86e-108: 389: 28.65		PKHA5_HUMAN (2-653): 1.62e-36: 150: 17.61
+	Hs
		521574 ACTN1_HUMAN (5-364): 3.89e-117: 397: 27.15		RHG24_HUMAN (55-181): 6.43e-27: 119: 25.93
+	Hs
		211612 ACTN4_HUMAN (12-364): 9.99e-114: 388: 26.58		RHG24_HUMAN (55-181): 6.43e-27: 119: 25.93